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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2859
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Id2
Name: inhibitor of DNA binding 2
Acc ID: CHEBI:15367
Term: all-trans-retinoic acid
Definition: A retinoic acid in which all four exocyclic double bonds have E- (trans-) geometry.
Chemical ID: MESH:D014212
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Id2affects expressionISOID2 (Homo sapiens)6480464CTDTretinoin affects the expression of ID2 mRNAPMID:16054129
Id2decreases expressionISOID2 (Homo sapiens)6480464CTDTretinoin results in decreased expression of ID2 mRNAPMID:17310985
Id2increases expressionISOID2 (Homo sapiens)6480464CTDTretinoin results in increased expression of ID2 mRNAPMID:15894607 PMID:16129123 PMID:16494909 PMID:17138961 PMID:17218384 PMID:23724009 PMID:33167477
Id2multiple interactionsISOID2 (Homo sapiens)6480464CTD[Tretinoin co-treated with arsenic trioxide] results in increased expression of ID2 mRNAPMID:15894607
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