GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Hspa5 | increases expression | EXP | | 6480464 | CTD | Palmitic Acid results in increased expression of HSPA5 mRNA | PMID:24349266 PMID:34979142 | Hspa5 | multiple interactions | EXP | | 6480464 | CTD | [7-hydroxycoumarin co-treated with Palmitic Acid] results in increased expression of HSPA5 mRNA; [Scopoletin co-treated with Palmitic Acid] results in increased expression of HSPA5 mRNA | PMID:34979142 | Hspa5 | increases expression | ISO | Hspa5 (Mus musculus) | 6480464 | CTD | Palmitic Acid results in increased expression of HSPA5 mRNA; Palmitic Acid results in increased expression of HSPA5 protein | PMID:26655953 PMID:30208301 PMID:36030031 | Hspa5 | increases expression | ISO | HSPA5 (Homo sapiens) | 6480464 | CTD | Palmitic Acid results in increased expression of HSPA5 protein | PMID:30738135 | Hspa5 | multiple interactions | ISO | Hspa5 (Mus musculus) | 6480464 | CTD | 4-phenylbutyric acid inhibits the reaction [Palmitic Acid results in increased expression of HSPA5 mRNA]; 4-phenylbutyric acid inhibits the reaction [Palmitic Acid results in increased expression of HSPA5 protein]; [Oleic Acid co-treated with Palmitic Acid] results in increased expression of HSPA5 protein; BACE1 protein affects the reaction [SNHG14 affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of HSPA5 protein]]; MIR497 affects the reaction [SNHG14 affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of HSPA5 protein]]; obeticholic acid inhibits the reaction [Palmitic Acid results in increased expression of HSPA5 protein]; SNHG14 affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of HSPA5 protein]; trigonelline inhibits the reaction [Palmitic Acid results in increased expression of HSPA5 protein] | PMID:26655953 PMID:30208301 PMID:36030031 PMID:37009739 | Hspa5 | multiple interactions | ISO | HSPA5 (Homo sapiens) | 6480464 | CTD | [Palmitic Acid co-treated with Oleic Acid] affects the expression of HSPA5 mRNA | PMID:30547786 | | ||||||||||||||||||||||
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