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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2835
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Hsd11b2
Name: hydroxysteroid 11-beta dehydrogenase 2
Acc ID: CHEBI:4315
Term: danazol
Definition: A terminal acetylenic compound that has formula C22H27NO2.
Chemical ID: MESH:D003613
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Hsd11b2decreases activityISOHSD11B2 (Homo sapiens)6480464CTDDanazol results in decreased activity of HSD11B2 proteinPMID:22273746
Hsd11b2multiple interactionsISOHSD11B2 (Homo sapiens)6480464CTDDanazol inhibits the reaction [HSD11B2 protein results in decreased activity of Glucocorticoids]PMID:22273746
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