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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2806
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Hmox1
Name: heme oxygenase 1
Acc ID: CHEBI:37659
Term: oleanolic acid
Definition: A pentacyclic triterpenoid that is olean-12-en-28-oic acid substituted by a beta-hydroxy group at position 3.
Chemical ID: MESH:D009828
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Hmox1multiple interactionsEXP 6480464CTDOleanolic Acid inhibits the reaction [Ethanol results in decreased expression of HMOX1 protein]PMID:25111957
Hmox1increases expressionISOHmox1 (Mus musculus)6480464CTDOleanolic Acid results in increased expression of HMOX1 mRNAPMID:18706400 PMID:19283895
Hmox1increases expressionISOHMOX1 (Homo sapiens)6480464CTDOleanolic Acid results in increased expression of HMOX1 proteinPMID:35690101
Hmox1multiple interactionsISOHmox1 (Mus musculus)6480464CTDOleanolic Acid inhibits the reaction [Phalloidine results in increased expression of HMOX1 mRNA]PMID:25280775
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