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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2679
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Gfap
Name: glial fibrillary acidic protein
Acc ID: CHEBI:3423
Term: carmustine
Definition: A member of the class of N-nitrosoureas that is 1,3-bis(2-chloroethyl)urea in which one of the nitrogens is substituted by a nitroso group.
Chemical ID: MESH:D002330
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Gfapdecreases expressionEXP 6480464CTDCarmustine results in decreased expression of GFAP proteinPMID:17572393
Gfapmultiple interactionsEXP 6480464CTDMelatonin inhibits the reaction [Carmustine results in decreased expression of GFAP protein]PMID:17572393
Gfapdecreases expressionISOGFAP (Homo sapiens)6480464CTDCarmustine results in decreased expression of GFAP mRNAPMID:15980968
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