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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2626
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Fos
Name: Fos proto-oncogene, AP-1 transcription factor subunit
Acc ID: CHEBI:41072
Term: 3-\{1-[3-(dimethylamino)propyl]-1H-indol-3-yl\}-4-(1H-indol-3-yl)-1H-pyrrole-2,5-dione
Definition: An indole that has formula C25H24N4O2.
Chemical ID: MESH:C070515
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Fosmultiple interactionsEXP 6480464CTDbisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of FOS mRNA]PMID:11687581
Fosmultiple interactionsISOFos (Mus musculus)6480464CTDbisindolylmaleimide I inhibits the reaction [cypermethrin results in increased expression of FOS protein]PMID:29149324
Fosmultiple interactionsISOFOS (Homo sapiens)6480464CTDbisindolylmaleimide I inhibits the reaction [[Dopamine co-treated with SLC6A3 protein] results in increased expression of FOS protein]PMID:12112414
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