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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2611
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Fgfr2
Name: fibroblast growth factor receptor 2
Acc ID: CHEBI:16236
Term: ethanol
Definition: A primary alcohol that is ethane in which one of the hydrogens is substituted by a hydroxy group.
Chemical ID: MESH:D000431
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Fgfr2multiple interactionsEXP 155882535RGDEthanol inhibits the reaction [FGF2 protein increases phosphorylation of Fgfr2 protein in aortic smooth muscle cells] 
Fgfr2decreases expressionEXP 6480464CTDEthanol results in decreased expression of FGFR2 proteinPMID:16770775
Fgfr2affects expressionISOFgfr2 (Mus musculus)6480464CTDEthanol affects the expression of FGFR2 mRNAPMID:30319688
Fgfr2increases expressionISOFgfr2 (Mus musculus)6480464CTDEthanol results in increased expression of FGFR2 mRNAPMID:30319688
Fgfr2increases expressionISOFGFR2 (Homo sapiens)6480464CTDEthanol results in increased expression of FGFR2 mRNAPMID:12720008
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