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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2587
Species: Rattus norvegicus
RGD Object: Gene
Symbol: F3
Name: coagulation factor III, tissue factor
Acc ID: CHEBI:73158
Term: sirtinol
Definition: A benzamide obtained by formal condensation of the carboxy group of 2-{[(2-hydroxy-1-naphthyl)methylene]amino}benzoic acid with the amino group of 1-phenylethylamine.
Chemical ID: MESH:C439060
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
F3multiple interactionsISOF3 (Homo sapiens)6480464CTDsirtinol promotes the reaction [TNF protein results in increased expression of F3 mRNA]; sirtinol promotes the reaction [TNF protein results in increased expression of F3 protein]PMID:20978007
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