A 3-hydroxy steroid that is estradiol substituted by a ethynyl group at position 17. It is a xenoestrogen synthesized from estradiol and has been shown to exhibit high estrogenic potency on oral administration.
Chemical ID:
MESH:D004997
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Ethinyl Estradiol results in decreased expression of ESR1; Ethinyl Estradiol results in decreased expression of ESR1 mRNA; Ethinyl Estradiol results in decreased expression of ESR1 protein
[Ethinyl Estradiol co-treated with Triclosan] results in decreased expression of ESR1 mRNA; Benzo(a)pyrene affects the reaction [Ethinyl Estradiol results in decreased expression of ESR1 protein]; fulvestrant inhibits the reaction [[Ethinyl Estradiol co-treated with Triclosan] results in decreased expression of ESR1 mRNA]; fulvestrant inhibits the reaction [Ethinyl Estradiol results in decreased expression of ESR1 mRNA]; fulvestrant inhibits the reaction [Ethinyl Estradiol results in decreased expression of ESR1 protein]; Tretinoin inhibits the reaction [Ethinyl Estradiol results in decreased expression of ESR1 mRNA]
[Ethinyl Estradiol co-treated with ESR1 protein] inhibits the reaction [IL1B protein results in increased expression of BCL3 mRNA]; [Ethinyl Estradiol co-treated with ESR1 protein] inhibits the reaction [IL1B protein results in increased expression of CISH mRNA]; [Ethinyl Estradiol co-treated with ESR1 protein] inhibits the reaction [IL1B protein results in increased expression of CXCL5 mRNA]; [Ethinyl Estradiol co-treated with ESR1 protein] inhibits the reaction [IL1B protein results in increased expression of NR0B2 mRNA]; [Ethinyl Estradiol co-treated with ESR1 protein] inhibits the reaction [IL1B protein results in increased expression of PLK3 mRNA]; [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of ESR1 mRNA; ESR1 gene mutant form inhibits the reaction [Ethinyl Estradiol results in decreased expression of and results in decreased secretion of INS1 protein]; ESR1 gene mutant form inhibits the reaction [Ethinyl Estradiol results in decreased expression of CARTPT mRNA]; ESR1 gene mutant form inhibits the reaction [Ethinyl Estradiol results in decreased expression of CD36 mRNA]; ESR1 gene mutant form inhibits the reaction [Ethinyl Estradiol results in decreased expression of CYP3A11 mRNA]; ESR1 gene mutant form inhibits the reaction [Ethinyl Estradiol results in decreased expression of CYP7A1 mRNA]; ESR1 gene mutant form inhibits the reaction [Ethinyl Estradiol results in decreased expression of NPY mRNA]; ESR1 gene mutant form inhibits the reaction [Ethinyl Estradiol results in decreased expression of TRPC5 mRNA]; ESR1 gene mutant form inhibits the reaction [Ethinyl Estradiol results in increased expression of ABCB11 mRNA]; ESR1 gene mutant form inhibits the reaction [Ethinyl Estradiol results in increased expression of CACNA1G mRNA]; ESR1 gene mutant form inhibits the reaction [Ethinyl Estradiol results in increased expression of CACNA1H mRNA]; ESR1 gene mutant form inhibits the reaction [Ethinyl Estradiol results in increased expression of CACNA1I mRNA]; ESR1 gene mutant form inhibits the reaction [Ethinyl Estradiol results in increased expression of GHSR mRNA]; ESR1 gene mutant form inhibits the reaction [Ethinyl Estradiol results in increased expression of INSR mRNA]; ESR1 gene mutant form inhibits the reaction [Ethinyl Estradiol results in increased expression of KCNQ2 mRNA]; ESR1 gene mutant form inhibits the reaction [Ethinyl Estradiol results in increased expression of KCNQ3 mRNA]; ESR1 gene mutant form inhibits the reaction [Ethinyl Estradiol results in increased expression of KCNQ5 mRNA]; ESR1 gene mutant form inhibits the reaction [Ethinyl Estradiol results in increased expression of LEPR mRNA]; ESR1 gene mutant form inhibits the reaction [Ethinyl Estradiol results in increased expression of NR0B2 mRNA]; ESR1 gene mutant form inhibits the reaction [Ethinyl Estradiol results in increased expression of PPARG mRNA]; ESR1 gene mutant form inhibits the reaction [Ethinyl Estradiol results in increased expression of TRPC5 mRNA]; ESR1 protein promotes the reaction [Ethinyl Estradiol results in decreased expression of ABCB11 mRNA]; ESR1 protein promotes the reaction [Ethinyl Estradiol results in decreased expression of ABCG5 mRNA]; ESR1 protein promotes the reaction [Ethinyl Estradiol results in decreased expression of ABCG8 mRNA]; ESR1 protein promotes the reaction [Ethinyl Estradiol results in decreased expression of CYP7A1 mRNA]; ESR1 protein promotes the reaction [Ethinyl Estradiol results in decreased expression of CYP8B1 mRNA]; ESR1 protein promotes the reaction [Ethinyl Estradiol results in decreased expression of SLC10A1 mRNA]; ESR1 protein promotes the reaction [Ethinyl Estradiol results in decreased expression of SLCO1A1 mRNA]; ESR1 protein promotes the reaction [Ethinyl Estradiol results in decreased expression of SLCO1B2 mRNA]; ESR1 protein promotes the reaction [Ethinyl Estradiol results in increased expression of CYP7B1 mRNA]; Ethinyl Estradiol binds to and results in increased activity of ESR1 protein; Ethinyl Estradiol inhibits the reaction [Streptozocin results in decreased expression of ESR1 mRNA]
ESR1 protein promotes the reaction [Ethinyl Estradiol results in decreased expression of SCARB1 protein modified form]; ESR1 protein promotes the reaction [Ethinyl Estradiol results in increased expression of SCARB2 protein modified form]; Ethinyl Estradiol analog promotes the reaction [ESR1 protein modified form binds to NCOA1 protein modified form]; Ethinyl Estradiol analog promotes the reaction [ESR1 protein modified form binds to NRIP1 protein modified form]; Ethinyl Estradiol binds to and results in increased activity of ESR1 protein; Ethinyl Estradiol inhibits the reaction [Estradiol binds to ESR1 protein]; Ethinyl Estradiol promotes the reaction [ESR1 protein binds to ESR1 protein]
