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GENE - TERM ANNOTATION REPORT

RGD ID: 2543
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Egfr
Name: epidermal growth factor receptor
Acc ID: GO:0007173
Term: epidermal growth factor receptor signaling pathway
Definition: The series of molecular signals initiated by binding of a ligand to the tyrosine kinase receptor EGFR (ERBB1) on the surface of a cell. The pathway ends with regulation of a downstream cellular process, e.g. transcription.
Definition Source(s): GOC:ceb
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Egfr IDA 70386RGD  
Egfr IMP 1581908RGD  
Egfracts_upstream_of_or_withinISOEgfr (Mus musculus)1624291RGDMGI:95290 PMID:14712229 PMID:15695332 PMID:17686994 PMID:7641815

PMID:14712229 PMID:15695332 PMID:17686994 PMID:7641815
Egfracts_upstream_of_or_withinISOEGFR (Homo sapiens)1624291RGD PMID:7736574

PMID:7736574
Egfrinvolved_inISOEgfr (Mus musculus)1624291RGDMGI:107508 MGI:3763534 PMID:12399441 PMID:12761849 PMID:23333074 PMID:23899604 PMID:28783046 PMID:30770250 PMID:6248866 PMID:7678348 PMID:7752576 PMID:8456283 PMID:8702723 PMID:9556621

PMID:12399441 PMID:12761849 PMID:23333074 PMID:23899604 PMID:28783046 PMID:30770250 PMID:6248866 PMID:7678348 PMID:7752576 PMID:8456283 PMID:8702723 PMID:9556621
Egfrinvolved_inISOEGFR (Homo sapiens)1624291RGD PMID:12435727 PMID:12828935 PMID:17655843 PMID:20878056 PMID:9890893

PMID:12435727 PMID:12828935 PMID:17655843 PMID:20878056 PMID:9890893
Egfrinvolved_inIDA 8553583UniProtPMID:20639532

 
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