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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2480
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cyp4b1
Name: cytochrome P450, family 4, subfamily b, polypeptide 1
Acc ID: CHEBI:34568
Term: Benzo[ghi]perylene
Definition: An ortho- and peri-fused polycyclic arene that has formula C22H12.
Chemical ID: MESH:C006718
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cyp4b1increases expressionISOCYP4B1 (Homo sapiens)6480464CTD1,12-benzoperylene results in increased expression of CYP4B1PMID:27234499
Cyp4b1multiple interactionsISOCYP4B1 (Homo sapiens)6480464CTD2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [1,12-benzoperylene results in increased expression of CYP4B1]PMID:27234499
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