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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2465
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cyp2a3
Name: cytochrome P450, family 2, subfamily a, polypeptide 3
Acc ID: CHEBI:16243
Term: quercetin
Definition: A pentahydroxyflavone having the five hydroxy groups placed at the 3-, 3'-, 4'-, 5- and 7-positions. It is one of the most abundant flavonoids in edible vegetables, fruit and wine.
Chemical ID: MESH:D011794
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cyp2a3decreases activityISOCyp2a4 (Mus musculus)6480464CTDQuercetin results in decreased activity of CYP2A4 proteinPMID:18420780
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