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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2459
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cyp1a2
Name: cytochrome P450, family 1, subfamily a, polypeptide 2
Acc ID: CHEBI:82285
Term: ortho-Aminoazotoluene
Definition: An azobenzene that has formula C14H15N3.
Chemical ID: MESH:D009762
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cyp1a2increases activityISOCyp1a2 (Mus musculus)6480464CTDo-Aminoazotoluene results in increased activity of CYP1A2 proteinPMID:15863256
Cyp1a2increases expressionISOCyp1a2 (Mus musculus)6480464CTDo-Aminoazotoluene results in increased expression of CYP1A2 mRNAPMID:10887293 PMID:14562683
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