GENE - CHEMICAL INTERACTIONS REPORT
RGD ID:
2459
Species:
Rattus norvegicus
RGD Object:
Gene
Symbol:
Cyp1a2
Name:
cytochrome P450, family 1, subfamily a, polypeptide 2
Acc ID:
CHEBI:81508
Term:
2,3,4,7,8-Pentachlorodibenzofuran
Definition:
A dibenzofuran that has formula C12H3Cl5O.
Chemical ID:
MESH:C038890
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Cyp1a2 increases activity EXP 6480464 CTD 2,3,4,7,8-pentachlorodibenzofuran results in increased activity of CYP1A2 protein PMID:17160103 PMID:20705892 Cyp1a2 increases expression EXP 6480464 CTD 2,3,4,7,8-pentachlorodibenzofuran results in increased expression of CYP1A2 mRNA PMID:20705892 PMID:21724226 Cyp1a2 multiple interactions EXP 6480464 CTD [Tetrachlorodibenzodioxin co-treated with 2,3,4,7,8-pentachlorodibenzofuran co-treated with 3,4,5,3',4'-pentachlorobiphenyl] results in increased activity of CYP1A2 protein PMID:17342195 Cyp1a2 affects abundance ISO Cyp1a2 (Mus musculus) 6480464 CTD CYP1A2 protein affects the abundance of 2,3,4,7,8-pentachlorodibenzofuran PMID:10448125 PMID:9240455 Cyp1a2 increases activity ISO CYP1A2 (Homo sapiens) 6480464 CTD 2,3,4,7,8-pentachlorodibenzofuran results in increased activity of CYP1A2 protein PMID:20705892 Cyp1a2 increases expression ISO Cyp1a2 (Mus musculus) 6480464 CTD 2,3,4,7,8-pentachlorodibenzofuran results in increased expression of CYP1A2 mRNA PMID:23674508 PMID:24713691 Cyp1a2 increases expression ISO CYP1A2 (Homo sapiens) 6480464 CTD 2,3,4,7,8-pentachlorodibenzofuran results in increased expression of CYP1A2 mRNA PMID:20705892 
