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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2326
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cebpa
Name: CCAAT/enhancer binding protein alpha
Acc ID: CHEBI:18723
Term: nicotine
Definition: A racemate composed of equimolar amounts of (R)- and (S)-nicotine.
Chemical ID: MESH:D009538
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cebpaaffects expressionEXP 6480464CTDNicotine affects the expression of CEBPA mRNAPMID:31972234
Cebpamultiple interactionsEXP 6480464CTD[Nicotine results in increased abundance of Cotinine] which results in increased expression of CEBPA proteinPMID:29617909
Cebpaincreases expressionISOCebpa (Mus musculus)6480464CTDNicotine results in increased expression of CEBPA mRNAPMID:31622651
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