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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2319
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cdk1
Name: cyclin-dependent kinase 1
Acc ID: CHEBI:10058
Term: Xanthatin
Definition: A sesquiterpene lactone that has formula C15H18O3.
Chemical ID: MESH:C022186
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cdk1decreases expressionISOCDK1 (Homo sapiens)6480464CTDxanthatin results in decreased expression of CDK1 mRNAPMID:21568272
Cdk1increases phosphorylationISOCDK1 (Homo sapiens)6480464CTDxanthatin results in increased phosphorylation of CDK1 proteinPMID:29074359
Cdk1multiple interactionsISOCDK1 (Homo sapiens)6480464CTDGo 6976 inhibits the reaction [xanthatin results in increased phosphorylation of CDK1 protein]PMID:29074359
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