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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2295243
Species: Mus musculus
RGD Object: Gene
Symbol: H3f4
Name: H3.4 histone, cluster member
Acc ID: CHEBI:18248
Term: iron atom
Definition: An iron group element atom that has atomic number 26.
Chemical ID: MESH:D007501
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
H3f4increases methylationISOH3-4 (Homo sapiens)6480464CTDIron results in increased methylation of H3-4 proteinPMID:21385672
H3f4multiple interactionsISOH3-4 (Homo sapiens)6480464CTD[[Iron co-treated with Ketoglutaric Acids] results in increased activity of KDM3A protein] which results in decreased methylation of H3-4 proteinPMID:16603237
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