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Gene: H3-4 (H3.4 histone) Homo sapiens
Symbol: H3-4
Name: H3.4 histone
RGD ID: 1317808
Description: Predicted to have DNA binding activity and protein heterodimerization activity. Involved in nucleosome assembly. Localizes to nuclear nucleosome.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: H3 histone family, member T; H3.4; H3/g; H3/t; H3FT; H3t; HIST3H3; histone 3, H3; histone cluster 3 H3; histone cluster 3, H3; histone H3.1t; histone H3.4; MGC126886; MGC126888
Mus musculus (house mouse) : H3f4 (H3.4 histone)  MGI
Rattus norvegicus (Norway rat) : H3f4 (H3.4 histone)  Alliance
Pan paniscus (bonobo/pygmy chimpanzee) : LOC100974795 (histone H3.1t)
Canis lupus familiaris (dog) : H3-4 (H3.4 histone)
Sus scrofa (pig) : LOC110259305 (histone H3.1)
Chlorocebus sabaeus (African green monkey) : HIST3H3 (histone cluster 3, H3)
Heterocephalus glaber (naked mole-rat) : LOC101721281 (histone H3.1)
more info ...
Related Pseudogenes: H3P15   H3P45  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl1228,424,845 - 228,425,325 (-)EnsemblGRCh38hg38GRCh38
GRCh38.p13 Ensembl1228,424,845 - 228,425,360 (-)EnsemblGRCh38hg38GRCh38
GRCh381228,424,845 - 228,425,360 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371228,612,546 - 228,613,026 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361226,679,169 - 226,679,649 (-)NCBINCBI36hg18NCBI36
Build 341224,919,280 - 224,919,761NCBI
Celera1201,802,501 - 201,802,981 (-)NCBI
Cytogenetic Map1q42.13NCBI
HuRef1199,127,141 - 199,127,621 (-)NCBIHuRef
CHM1_11229,884,858 - 229,885,338 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on H3-4
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1317808
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2020-09-16
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.