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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2275
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Casp3
Name: caspase 3
Acc ID: CHEBI:9588
Term: ticlopidine
Definition: A thienopyridine that is 4,5,6,7-tetrahydrothieno[3,2-c]pyridine in which the hydrogen attached to the nitrogen is replaced by an o-chlorobenzyl group.
Chemical ID: MESH:D013988
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Casp3increases activityISOCASP3 (Homo sapiens)6480464CTDTiclopidine results in increased activity of CASP3 proteinPMID:22700542
Casp3multiple interactionsISOCASP3 (Homo sapiens)6480464CTDPalmitic Acid promotes the reaction [Ticlopidine results in increased activity of CASP3 protein]PMID:22700542
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