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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2275
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Casp3
Name: caspase 3
Acc ID: CHEBI:9126
Term: Sesamol
Definition: A benzodioxole that has formula C7H6O3.
Chemical ID: MESH:C025583
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Casp3multiple interactionsEXP 6480464CTDsesamol inhibits the reaction [Aluminum Oxide results in increased expression of CASP3 mRNA]PMID:35403826
Casp3increases activityISOCASP3 (Homo sapiens)6480464CTDsesamol results in increased activity of CASP3 proteinPMID:27270451
Casp3multiple interactionsISOCasp3 (Mus musculus)6480464CTDsesamol inhibits the reaction [Lipopolysaccharides results in increased activity of CASP3 protein]; zinc protoporphyrin inhibits the reaction [sesamol inhibits the reaction [Lipopolysaccharides results in increased activity of CASP3 protein]]PMID:30261164
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