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GENE - TERM ANNOTATION REPORT

RGD ID: 2201
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Bdkrb2
Name: bradykinin receptor B2
Acc ID: GO:1990127
Term: intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator
Definition: The series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway is induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, in response to the detection of osmotic stress, and ends when the execution phase of apoptosis is triggered.
Definition Source(s): GOC:krc, GOC:mtg_apoptosis, PMID:16571598
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Bdkrb2acts_upstream_ofISOBdkrb2 (Mus musculus)1624291RGDMGI:98834 MGI:99702 PMID:16571598

PMID:16571598
Bdkrb2involved_inIEAUniProtKB:P32299 or ensembl:ENSMUSP000000016521600115EnsemblGO_REF:0000107

GO_REF:0000107
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