GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Bcl2 | increases expression | EXP | | 6480464 | CTD | 4-phenylbutyric acid results in increased expression of BCL2 protein | PMID:33651226 | Bcl2 | multiple interactions | EXP | | 6480464 | CTD | 4-phenylbutyric acid inhibits the reaction [alpha-Chlorohydrin results in decreased expression of BCL2 protein]; 4-phenylbutyric acid inhibits the reaction [Methamphetamine results in decreased expression of BCL2 protein] | PMID:33651226 PMID:34214594 | Bcl2 | multiple interactions | ISO | Bcl2 (Mus musculus) | 6480464 | CTD | 4-phenylbutyric acid inhibits the reaction [dibromoacetonitrile results in decreased expression of BCL2 protein] | PMID:38065397 | Bcl2 | multiple interactions | ISO | BCL2 (Homo sapiens) | 6480464 | CTD | 4-phenylbutyric acid inhibits the reaction [Silver Compounds results in decreased expression of BCL2 protein]; 4-phenylbutyric acid inhibits the reaction [tris(1,3-dichloro-2-propyl)phosphate results in decreased expression of BCL2 protein]; 4-phenylbutyric acid promotes the reaction [Acetylcysteine inhibits the reaction [tris(1,3-dichloro-2-propyl)phosphate results in decreased expression of BCL2 protein]]; Acetylcysteine promotes the reaction [4-phenylbutyric acid inhibits the reaction [tris(1,3-dichloro-2-propyl)phosphate results in decreased expression of BCL2 protein]] | PMID:27816613 PMID:29306025 | |
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