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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2192
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Bax
Name: BCL2 associated X, apoptosis regulator
Acc ID: CHEBI:8499
Term: propranolol
Definition: A propanolamine that is propan-2-ol substituted by a propan-2-ylamino group at position 1 and a naphthalen-1-yloxy group at position 3.
Chemical ID: MESH:D011433
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Baxdecreases expressionEXP 6480464CTDPropranolol results in decreased expression of BAX mRNAPMID:11218852
Baxincreases expressionEXP 6480464CTDPropranolol results in increased expression of BAX proteinPMID:35738838
Baxmultiple interactionsEXP 6480464CTDFat Emulsions, Intravenous inhibits the reaction [Propranolol results in increased expression of BAX protein]PMID:35738838
Baxincreases expressionISOBAX (Homo sapiens)6480464CTDPropranolol results in increased expression of BAX proteinPMID:31838054
Baxmultiple interactionsISOBax (Mus musculus)6480464CTDPropranolol inhibits the reaction [Arsenic Trioxide results in increased expression of BAX protein]PMID:36707890
Baxmultiple interactionsISOBAX (Homo sapiens)6480464CTDANGPT2 protein inhibits the reaction [Propranolol results in increased expression of BAX protein]PMID:31838054
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