GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Bax | increases expression | EXP | | 6480464 | CTD | Isoproterenol results in increased expression of BAX mRNA; Isoproterenol results in increased expression of BAX protein | PMID:16116328 PMID:17961425 PMID:27491814 PMID:29414845 PMID:30152906 PMID:32007421 PMID:33210414 PMID:33242989 PMID:35430261 PMID:36593721 PMID:37806379 | Bax | multiple interactions | EXP | | 6480464 | CTD | 2-chloro-5-nitrobenzanilide promotes the reaction [[Streptozocin co-treated with Isoproterenol] affects the expression of BAX protein]; [Acrolein results in increased susceptibility to Isoproterenol] which results in increased expression of BAX protein; [Streptozocin co-treated with Isoproterenol] affects the expression of BAX protein; Acrolein promotes the reaction [Isoproterenol results in increased expression of BAX mRNA]; Acrolein promotes the reaction [Isoproterenol results in increased expression of BAX protein]; anethole inhibits the reaction [Isoproterenol results in increased expression of BAX mRNA]; Apigenin inhibits the reaction [Isoproterenol results in increased expression of BAX protein]; erdosteine inhibits the reaction [Isoproterenol results in increased expression of BAX protein]; Hesperidin inhibits the reaction [2-chloro-5-nitrobenzanilide promotes the reaction [[Streptozocin co-treated with Isoproterenol] affects the expression of BAX protein]]; Hesperidin inhibits the reaction [[Streptozocin co-treated with Isoproterenol] affects the expression of BAX protein]; Plant Extracts inhibits the reaction [[Acrolein results in increased susceptibility to Isoproterenol] which results in increased expression of BAX protein]; Plant Extracts inhibits the reaction [Acrolein promotes the reaction [Isoproterenol results in increased expression of BAX mRNA]]; Plant Extracts inhibits the reaction [Acrolein promotes the reaction [Isoproterenol results in increased expression of BAX protein]]; protocatechuic acid inhibits the reaction [Isoproterenol results in increased expression of BAX protein]; punicalagin inhibits the reaction [Isoproterenol results in increased expression of BAX protein]; Rosuvastatin Calcium inhibits the reaction [Isoproterenol results in increased expression of BAX mRNA]; Tretinoin inhibits the reaction [Isoproterenol results in increased expression of BAX mRNA]; zingiberene inhibits the reaction [Isoproterenol results in increased expression of BAX protein] | PMID:24954035 PMID:29414845 PMID:30152906 PMID:32007421 PMID:33210414 PMID:33242989 PMID:35430261 PMID:36593721 PMID:37806379 | Bax | decreases expression | ISO | BAX (Homo sapiens) | 6480464 | CTD | Isoproterenol results in decreased expression of BAX mRNA | PMID:24286936 | Bax | increases expression | ISO | Bax (Mus musculus) | 6480464 | CTD | Isoproterenol results in increased expression of BAX protein | PMID:15052282 | | ||||||||||||||||||||||
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