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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2192
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Bax
Name: BCL2 associated X, apoptosis regulator
Acc ID: CHEBI:50686
Term: atorvastatin calcium
Definition: An organic calcium salt composed of calcium cations and atorvastatin anions in a 1:2 ratio.
Chemical ID: MESH:D000069059
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Baxincreases expressionISOBAX (Homo sapiens)6480464CTDAtorvastatin results in increased expression of BAX proteinPMID:19935899
Baxmultiple interactionsISOBax (Mus musculus)6480464CTDAtorvastatin inhibits the reaction [[APOE protein affects the susceptibility to Dietary Fats] which affects the expression of BAX protein]PMID:37121058
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