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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2153
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Arnt
Name: aryl hydrocarbon receptor nuclear translocator
Acc ID: CHEBI:34887
Term: nickel dichloride
Definition: A compound of nickel and chloride in which the ratio of nickel (in the +2 oxidation state) to chloride is 1:2.
Chemical ID: MESH:C022838
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Arntmultiple interactionsISOArnt (Mus musculus)6480464CTDHIF1A affects the reaction [nickel chloride results in increased expression of ARNT mRNA]PMID:12729255
Arntmultiple interactionsISOARNT (Homo sapiens)6480464CTDnickel chloride promotes the reaction [HIF1A protein binds to ARNT protein]PMID:29355601
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