GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Agt | increases expression | ISO | AGT (Homo sapiens) | 6480464 | CTD | Sildenafil Citrate results in increased expression of AGT protein modified form | PMID:15613622 | Agt | multiple interactions | ISO | Agt (Mus musculus) | 6480464 | CTD | PRKG1 protein promotes the reaction [Sildenafil Citrate inhibits the reaction [AGT protein modified form results in increased expression of CCN2 mRNA]]; PRKG1 protein promotes the reaction [Sildenafil Citrate inhibits the reaction [AGT protein modified form results in increased expression of COL1A1 mRNA]]; PRKG1 protein promotes the reaction [Sildenafil Citrate inhibits the reaction [AGT protein modified form results in increased expression of FN1 mRNA]]; PRKG1 protein promotes the reaction [Sildenafil Citrate inhibits the reaction [AGT protein modified form results in increased expression of TGFB1 mRNA]]; Sildenafil Citrate inhibits the reaction [AGT protein modified form results in increased expression of CCN2 mRNA]; Sildenafil Citrate inhibits the reaction [AGT protein modified form results in increased expression of COL1A1 mRNA]; Sildenafil Citrate inhibits the reaction [AGT protein modified form results in increased expression of FN1 mRNA]; Sildenafil Citrate inhibits the reaction [AGT protein modified form results in increased expression of TGFB1 mRNA] | PMID:25139994 | | ||||||||||||||||||||||
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