GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Parp1 | increases activity | EXP | | 6480464 | CTD | Oxidopamine results in increased activity of PARP1 protein | PMID:21397656 | Parp1 | increases cleavage | EXP | | 6480464 | CTD | Oxidopamine results in increased cleavage of PARP1 protein | PMID:25446857 | Parp1 | multiple interactions | EXP | | 6480464 | CTD | 5,10,15,20-tetrakis(4-sulfonatophenyl)porphyrinato iron(III) chloride inhibits the reaction [Oxidopamine results in increased activity of PARP1 protein]; salvin inhibits the reaction [Oxidopamine results in increased cleavage of PARP1 protein] | PMID:21397656 PMID:25446857 | Parp1 | increases cleavage | ISO | PARP1 (Homo sapiens) | 6480464 | CTD | Oxidopamine results in increased cleavage of PARP1 protein | PMID:25446857 PMID:30707903 PMID:31705926 | Parp1 | increases cleavage | ISO | Parp1 (Mus musculus) | 6480464 | CTD | Oxidopamine results in increased cleavage of PARP1 protein | PMID:10397638 PMID:33571554 | Parp1 | increases expression | ISO | PARP1 (Homo sapiens) | 6480464 | CTD | Oxidopamine results in increased expression of PARP1 protein | PMID:31176653 | Parp1 | multiple interactions | ISO | PARP1 (Homo sapiens) | 6480464 | CTD | OPA1 protein affects the reaction [salvin inhibits the reaction [Oxidopamine results in increased cleavage of PARP1 protein]]; PINK1 protein affects the reaction [salvin inhibits the reaction [Oxidopamine results in increased cleavage of PARP1 protein]]; pyrazolanthrone inhibits the reaction [Oxidopamine results in increased cleavage of PARP1 protein]; salvin inhibits the reaction [Oxidopamine results in increased cleavage of PARP1 protein]; SB 203580 inhibits the reaction [Oxidopamine results in increased cleavage of PARP1 protein]; TH protein inhibits the reaction [Oxidopamine results in increased cleavage of PARP1 protein]; tricetin inhibits the reaction [Oxidopamine results in increased expression of PARP1 protein] | PMID:19815691 PMID:25446857 PMID:30707903 PMID:31176653 PMID:31705926 | Parp1 | multiple interactions | ISO | Parp1 (Mus musculus) | 6480464 | CTD | 2-chloro-5-hydroxyphenylglycine affects the reaction [Oxidopamine results in increased cleavage of PARP1 protein]; 6-methyl-2-(phenylethynyl)pyridine promotes the reaction [Oxidopamine results in increased cleavage of PARP1 protein]; GOPC protein affects the reaction [2-chloro-5-hydroxyphenylglycine affects the reaction [Oxidopamine results in increased cleavage of PARP1 protein]]; GOPC protein affects the reaction [6-methyl-2-(phenylethynyl)pyridine promotes the reaction [Oxidopamine results in increased cleavage of PARP1 protein]]; GOPC protein affects the reaction [Oxidopamine results in increased cleavage of PARP1 protein] | PMID:33571554 | |
Go Back to source page | Continue to Ontology report |