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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2053
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Parp1
Name: poly (ADP-ribose) polymerase 1
Acc ID: CHEBI:36560
Term: zinc oxide
Definition: A zinc molecular entity that has formula OZn.
Chemical ID: MESH:D015034
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Parp1increases cleavageISOParp1 (Mus musculus)6480464CTDZinc Oxide analog results in increased cleavage of PARP1 proteinPMID:24614525
Parp1multiple interactionsISOParp1 (Mus musculus)6480464CTDAcetylcysteine inhibits the reaction [Zinc Oxide analog results in increased cleavage of PARP1 protein]PMID:24614525
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