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GENE - TERM ANNOTATION REPORT

RGD ID: 18920996
Species: Heterocephalus glaber
RGD Object: Gene
Symbol: Il18
Name: interleukin 18
Acc ID: DOID:684
Term: hepatocellular carcinoma
Definition: A liver carcinoma that has_material_basis_in undifferentiated hepatocytes and located_in the liver. (DO)
Definition Source(s): http://cancergenome.nih.gov/cancersselected/LiverHepatocellularCarcinoma "DO" "DO", http://en.wikipedia.org/wiki/Hepatocellular_carcinoma "DO" "DO", http://www.omim.org/entry/114550 "DO" "DO"
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Il18disease_progressionISOIL18 (Homo sapiens)9068941RGD PMID:26893476 REF_RGD_ID:11538094
Il18disease_progressionISOIL18 (Homo sapiens)9068941RGDassociated with hepatitis B, chronic;DNA:SNP:promoter:-607C>A(human)PMID:27470888 REF_RGD_ID:14696663
Il18severityISOIL18 (Homo sapiens)9068941RGDassociated with hepatitis C;DNA:SNPs, haplotype:promoter:-607C>A, -137G>C(human)PMID:29341496 REF_RGD_ID:14695526
Il18susceptibilityISOIL18 (Homo sapiens)9068941RGDDNA:SNP:promoter:-137G>C(rs187238)(human)PMID:27429592 REF_RGD_ID:14695540
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