GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | FASLG | multiple interactions | EXP | | 6480464 | CTD | [Acetylcysteine results in decreased abundance of Reactive Oxygen Species] which results in decreased expression of FASLG mRNA; Acetylcysteine inhibits the reaction [[Cisplatin co-treated with FASLG protein] results in decreased expression of BID protein]; Acetylcysteine inhibits the reaction [[Cisplatin co-treated with FASLG protein] results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [[Cisplatin co-treated with FASLG protein] results in increased activity of CASP8 protein]; Acetylcysteine inhibits the reaction [[Cisplatin co-treated with FASLG protein] results in increased activity of CASP9 protein]; Acetylcysteine inhibits the reaction [Arachidonic Acid results in increased expression of FASLG protein]; Acetylcysteine inhibits the reaction [Biological Products results in increased expression of FASLG protein] | PMID:17574045 PMID:19720122 PMID:22429591 PMID:28219700 | FASLG | increases expression | ISO | Faslg (Rattus norvegicus) | 6480464 | CTD | Acetylcysteine results in increased expression of FASLG mRNA | PMID:26332274 | FASLG | multiple interactions | ISO | Fasl (Mus musculus) | 6480464 | CTD | Acetylcysteine inhibits the reaction [Azoxymethane results in increased expression of FASLG protein]; Acetylcysteine inhibits the reaction [Zinc results in increased expression of FASLG protein] | PMID:11864783 PMID:20431929 | FASLG | multiple interactions | ISO | Faslg (Rattus norvegicus) | 6480464 | CTD | [Atorvastatin co-treated with Acetylcysteine] inhibits the reaction [sodium arsenite results in increased expression of FASLG protein]; Acetylcysteine inhibits the reaction [beta-hexachlorocyclohexane results in increased expression of FASLG protein]; Acetylcysteine inhibits the reaction [Dichlorodiphenyl Dichloroethylene results in increased expression of FASLG mRNA]; Acetylcysteine inhibits the reaction [Dichlorodiphenyl Dichloroethylene results in increased expression of FASLG protein] | PMID:19644561 PMID:19760616 PMID:20946910 | | ||||||||||||||||||||||
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