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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1595785
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Rorc
Name: RAR-related orphan receptor C
Acc ID: CHEBI:49
Term: (+)-Tetrandrine
Definition: A bisbenzylisoquinoline alkaloid that has formula C38H42N2O6.
Chemical ID: MESH:C009438
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Rorcdecreases expressionISORorc (Mus musculus)6480464CTDtetrandrine results in decreased expression of RORC mRNAPMID:26640276
Rorcmultiple interactionsISORorc (Mus musculus)6480464CTDtetrandrine inhibits the reaction [COL2A1 protein results in increased expression of RORC mRNA]PMID:26640276
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