GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Mt2A | decreases response to substance | ISO | Mt2 (Mus musculus) | 6480464 | CTD | MT2 protein results in decreased susceptibility to Nickel | PMID:16166738 | Mt2A | increases expression | ISO | MT2A (Homo sapiens) | 6480464 | CTD | Nickel results in increased expression of MT2A mRNA; Nickel results in increased expression of MT2A protein | PMID:14971665 PMID:19097988 PMID:24768652 PMID:25583101 PMID:26378417 | Mt2A | increases response to substance | ISO | Mt2 (Mus musculus) | 6480464 | CTD | MT2 gene mutant form results in increased susceptibility to Nickel | PMID:16166738 | Mt2A | multiple interactions | ISO | MT2A (Homo sapiens) | 6480464 | CTD | Acetylcysteine inhibits the reaction [Nickel results in increased expression of MT2A mRNA]; N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [Nickel results in increased expression of MT2A mRNA] | PMID:19097988 | Mt2A | multiple interactions | ISO | Mt2 (Mus musculus) | 6480464 | CTD | MT2 affects the reaction [Nickel affects the expression of CALR3 mRNA]; MT2 affects the reaction [Nickel affects the expression of CANX mRNA]; MT2 affects the reaction [Nickel affects the expression of COPG2 mRNA]; MT2 affects the reaction [Nickel affects the expression of FBXL12 mRNA]; MT2 affects the reaction [Nickel affects the expression of GABARAPL2 mRNA]; MT2 affects the reaction [Nickel affects the expression of GRPEL1 mRNA]; MT2 affects the reaction [Nickel affects the expression of IPO4 mRNA]; MT2 affects the reaction [Nickel affects the expression of MARCHF2 mRNA]; MT2 affects the reaction [Nickel affects the expression of MRPS18A mRNA]; MT2 affects the reaction [Nickel affects the expression of PEX13 mRNA]; MT2 affects the reaction [Nickel affects the expression of PSMB7 mRNA]; MT2 affects the reaction [Nickel affects the expression of RAB32 mRNA]; MT2 affects the reaction [Nickel affects the expression of RNF11 mRNA]; MT2 affects the reaction [Nickel affects the expression of RNF114 mRNA]; MT2 affects the reaction [Nickel affects the expression of RNF13 mRNA]; MT2 affects the reaction [Nickel affects the expression of RNF19A mRNA]; MT2 affects the reaction [Nickel affects the expression of RPL15 mRNA]; MT2 affects the reaction [Nickel affects the expression of RPL19 mRNA]; MT2 affects the reaction [Nickel affects the expression of RPL29 mRNA]; MT2 affects the reaction [Nickel affects the expression of RPL35 mRNA]; MT2 affects the reaction [Nickel affects the expression of RPL36A mRNA]; MT2 affects the reaction [Nickel affects the expression of RPL4 mRNA]; MT2 affects the reaction [Nickel affects the expression of RPLP0 mRNA]; MT2 affects the reaction [Nickel affects the expression of RPS14 mRNA]; MT2 affects the reaction [Nickel affects the expression of RPS3 mRNA]; MT2 affects the reaction [Nickel affects the expression of RPS7 mRNA]; MT2 affects the reaction [Nickel affects the expression of SKP2 mRNA]; MT2 affects the reaction [Nickel affects the expression of SMURF2 mRNA]; MT2 affects the reaction [Nickel affects the expression of SNX1 mRNA]; MT2 affects the reaction [Nickel affects the expression of SNX12 mRNA]; MT2 affects the reaction [Nickel affects the expression of STX6 mRNA]; MT2 affects the reaction [Nickel affects the expression of UBB mRNA]; MT2 affects the reaction [Nickel affects the expression of VPS16 mRNA]; MT2 affects the reaction [Nickel affects the expression of VPS35 mRNA]; MT2 affects the reaction [Nickel affects the expression of YWHAB mRNA]; MT2 affects the reaction [Nickel affects the expression of ZBTB22 mRNA]; SFTPB protein affects the reaction [Nickel results in decreased expression of MT2 mRNA] | PMID:16166738 | | ||||||||||||||||||||||
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