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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1592081
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Mpo
Name: myeloperoxidase
Acc ID: CHEBI:232410
Term: 4-aminobenzhydrazide
Definition: null
Chemical ID: MESH:C034343
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Mpodecreases activityISOMPO (Homo sapiens)6480464CTD4-aminobenzhydrazide results in decreased activity of MPO proteinPMID:23994743 PMID:7772042
Mpomultiple interactionsISOMpo (Mus musculus)6480464CTD4-aminobenzhydrazide inhibits the reaction [Tobacco Smoke Pollution results in increased activity of MPO protein]PMID:32726580
Mpomultiple interactionsISOMPO (Homo sapiens)6480464CTD4-aminobenzhydrazide inhibits the reaction [[MPO protein results in increased oxidation of dibromoacetonitrile] which results in increased chemical synthesis of Cyanides]; 4-aminobenzhydrazide inhibits the reaction [MPO protein results in increased chemical synthesis of Hypochlorous Acid]; 4-aminobenzhydrazide inhibits the reaction [MPO protein results in increased oxidation of 3,3',5,5'-tetramethylbenzidine]; 4-aminobenzhydrazide inhibits the reaction [MPO protein results in increased oxidation of dibromoacetonitrile]; [4-aminobenzhydrazide results in decreased activity of MPO protein] which affects the susceptibility to 7-hydroxycoumarinPMID:23994743 PMID:25614581 PMID:7772042
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