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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1582881
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Wdr74
Name: WD repeat domain 74
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Wdr74increases expressionEXP 6480464CTDbisphenol A results in increased expression of WDR74 mRNAPMID:25181051
Wdr74affects expressionISOWDR74 (Homo sapiens)6480464CTDbisphenol A affects the expression of WDR74 mRNAPMID:30903817
Wdr74increases expressionISOWdr74 (Mus musculus)6480464CTDbisphenol A results in increased expression of WDR74 mRNAPMID:29161229
Wdr74multiple interactionsISOWDR74 (Homo sapiens)6480464CTD[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of WDR74 mRNAPMID:28628672
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