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Gene: Wdr74 (WD repeat domain 74) Mus musculus
Symbol: Wdr74
Name: WD repeat domain 74
Description: Involved in RNA metabolic process and blastocyst formation. Localizes to the nucleus. Predicted to colocalize with the nuclear exosome (RNase complex). Is expressed in 8-cell stage embryo; blastocyst; compacted morula; early conceptus; and secondary oocyte. Orthologous to human WDR74 (WD repeat domain 74); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; acrylamide.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 5730436H21Rik; AA407588; WD repeat-containing protein 74
Homo sapiens (human) : WDR74 (WD repeat domain 74)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Wdr74 (WD repeat domain 74)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Wdr74 (WD repeat domain 74)
Pan paniscus (bonobo/pygmy chimpanzee) : WDR74 (WD repeat domain 74)
Canis lupus familiaris (dog) : WDR74 (WD repeat domain 74)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Wdr74 (WD repeat domain 74)
Sus scrofa (pig) : WDR74 (WD repeat domain 74)
Chlorocebus sabaeus (green monkey) : WDR74 (WD repeat domain 74)
Heterocephalus glaber (naked mole-rat) : Wdr74 (WD repeat domain 74)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl198,735,827 - 8,740,624 (+)Ensembl
GRCm38198,735,795 - 8,740,624 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37198,810,329 - 8,815,114 (+)NCBIGRCm37mm9NCBIm37
MGSCv36198,802,884 - 8,807,669 (+)NCBImm8
Celera198,495,912 - 8,500,697 (+)NCBICelera
Cytogenetic Map19 ANCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Wdr74
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1553186
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.