Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: WDR74 (WD repeat domain 74) Homo sapiens
Symbol: WDR74
Name: WD repeat domain 74
Description: Involved in rRNA processing and ribosomal large subunit biogenesis. Localizes to nucleolus and nucleoplasm. Colocalizes with nuclear exosome (RNase complex); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3-isobutyl-1-methyl-7H-xanthine; 4,4'-sulfonyldiphenol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: FLJ10439; FLJ21730; NOP seven-associated protein 1; Nsa1; WD repeat-containing protein 74
Mus musculus (house mouse) : Wdr74 (WD repeat domain 74)  MGI  Alliance
Rattus norvegicus (Norway rat) : Wdr74 (WD repeat domain 74)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Wdr74 (WD repeat domain 74)
Pan paniscus (bonobo/pygmy chimpanzee) : WDR74 (WD repeat domain 74)
Canis lupus familiaris (dog) : WDR74 (WD repeat domain 74)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Wdr74 (WD repeat domain 74)
Sus scrofa (pig) : WDR74 (WD repeat domain 74)
Chlorocebus sabaeus (African green monkey) : WDR74 (WD repeat domain 74)
Heterocephalus glaber (naked mole-rat) : Wdr74 (WD repeat domain 74)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl1162,832,342 - 62,841,809 (-)EnsemblGRCh38hg38GRCh38
GRCh381162,832,905 - 62,841,809 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371162,600,380 - 62,608,044 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361162,356,960 - 62,364,204 (-)NCBINCBI36hg18NCBI36
Celera1151,134,558 - 51,137,689 (-)NCBI
Celera1159,929,980 - 59,931,022 (-)NCBI
Cytogenetic Map11q12.3NCBI
HuRef1158,929,412 - 58,936,657 (-)NCBIHuRef
CHM1_11162,483,419 - 62,490,670 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on WDR74
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1603395
Created: 2007-04-28
Species: Homo sapiens
Last Modified: 2020-03-24
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.