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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1566119
Species: Rattus norvegicus
RGD Object: Gene
Symbol: H2ax
Name: H2A.X variant histone
Acc ID: CHEBI:80025
Term: Salinomycin
Definition: A spiroketal that has formula C42H70O11.
Chemical ID: MESH:C010327
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
H2axdecreases expressionISOH2AX (Homo sapiens)6480464CTDsalinomycin results in decreased expression of H2AX mRNAPMID:35914560
H2axmultiple interactionsISOH2AX (Homo sapiens)6480464CTD[salinomycin co-treated with Calcitriol] results in decreased expression of H2AX mRNAPMID:35914560
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