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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1563119
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Mef2c
Name: myocyte enhancer factor 2C
Acc ID: CHEBI:9288
Term: streptozocin
Definition: An N-nitrosourea that is an antibiotic produced by Streptomyces achromogenes. It is used as an antineoplastic agent and to induce diabetes in experimental animals.
Chemical ID: MESH:D013311
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Mef2cdecreases expressionISOMef2c (Mus musculus)6480464CTDStreptozocin results in decreased expression of MEF2C mRNAPMID:27629361
Mef2cmultiple interactionsISOMEF2C (Homo sapiens)6480464CTDSOD1 protein inhibits the reaction [Streptozocin results in decreased expression of MEF2C mRNA]PMID:27629361
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