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GENE - TERM ANNOTATION REPORT

RGD ID: 1561168
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Lrrk2
Name: leucine-rich repeat kinase 2
Acc ID: DOID:0060368
Term: Parkinson's disease 2
Definition: An early-onset Parkinson's disease that has_material_basis_in mutation in the parkin gene on chromosome 6q25.2-q27. (DO)
Definition Source(s): https://www.ncbi.nlm.nih.gov/pubmed/22315721 "DO" "DO"
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Lrrk2 ISOLRRK2 (Homo sapiens)8554872ClinVarClinVar Annotator: match by term: Young-onset Parkinson diseasePMID:15680455 PMID:15680456 PMID:15680457 PMID:15726496 PMID:15732108 PMID:15811455 PMID:15852371 PMID:15929036 PMID:15955629 PMID:16001413 PMID:16102999 PMID:16115731 PMID:16145815 PMID:16157901 PMID:16172858 PMID:16240353 PMID:16269541 PMID:16311269 PMID:16401756 PMID:16436781 PMID:16436782 PMID:16533964 PMID:16728648 PMID:16750377 PMID:16960813 PMID:16966501 PMID:16966502 PMID:17050822 PMID:17060595 PMID:17215492 PMID:17353388 PMID:17938369 PMID:18539534 PMID:18539535 PMID:18704525 PMID:18981379 PMID:18986508 PMID:19020907 PMID:19283415 PMID:20008657 PMID:20197411 PMID:20301387 PMID:21115957 PMID:21280089 PMID:21753163 PMID:21850687 PMID:22539006 PMID:22575234 PMID:23075850 PMID:23472874 PMID:24033266 PMID:24148854 PMID:24243757 PMID:25330418 PMID:25741868 PMID:26062626 PMID:26251043 PMID:26467025 PMID:28465860 PMID:28492532 PMID:28639421 PMID:29386392 PMID:29402177
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