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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1552470
Species: Mus musculus
RGD Object: Gene
Symbol: Kifc1
Name: kinesin family member C1
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Kifc1affects expressionISOKIFC1 (Homo sapiens)6480464CTDbisphenol A affects the expression of KIFC1 mRNAPMID:30903817
Kifc1affects expressionISOKifc1 (Rattus norvegicus)6480464CTDbisphenol A affects the expression of KIFC1 mRNAPMID:25181051 PMID:32145629
Kifc1decreases expressionISOKIFC1 (Homo sapiens)6480464CTDbisphenol A results in decreased expression of KIFC1 mRNAPMID:29275510
Kifc1decreases expressionISOKifc1 (Rattus norvegicus)6480464CTDbisphenol A results in decreased expression of KIFC1 mRNAPMID:34947998
Kifc1decreases methylationISOKIFC1 (Homo sapiens)6480464CTDbisphenol A results in decreased methylation of KIFC1 genePMID:31601247
Kifc1multiple interactionsISOKIFC1 (Homo sapiens)6480464CTD[bisphenol A co-treated with Fulvestrant] results in decreased methylation of KIFC1 gene; bisphenol A promotes the reaction [KIFC1 protein binds to ESR1 protein]PMID:27156127 PMID:31601247
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