KIFC1 (kinesin family member C1) - Rat Genome Database

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Gene: KIFC1 (kinesin family member C1) Homo sapiens
Analyze
Symbol: KIFC1
Name: kinesin family member C1
RGD ID: 1349353
HGNC Page HGNC:6389
Description: Predicted to enable ATP hydrolysis activity; microtubule binding activity; and minus-end-directed microtubule motor activity. Involved in mitotic metaphase chromosome alignment and mitotic spindle assembly. Located in membrane.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: HSET; kinesin-like 2; kinesin-like protein 2; kinesin-like protein KIFC1; kinesin-related protein HSET; KNSL2; MGC1202; MGC149736; MGC149737
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38633,391,461 - 33,409,896 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl633,391,823 - 33,409,896 (+)EnsemblGRCh38hg38GRCh38
GRCh37633,359,600 - 33,377,673 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36633,467,583 - 33,485,625 (+)NCBINCBI36Build 36hg18NCBI36
Celera634,913,703 - 34,932,095 (+)NCBICelera
Cytogenetic Map6p21.32NCBI
HuRef633,101,381 - 33,119,773 (+)NCBIHuRef
CHM1_1633,361,187 - 33,379,567 (+)NCBICHM1_1
T2T-CHM13v2.0633,212,742 - 33,231,258 (+)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dimethylhydrazine  (ISO)
1-chloro-2,4-dinitrobenzene  (EXP)
1-naphthyl isothiocyanate  (ISO)
17beta-estradiol  (EXP,ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,2',5,5'-tetrachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2-palmitoylglycerol  (EXP)
3,3',4,4',5-pentachlorobiphenyl  (ISO)
4,4'-diaminodiphenylmethane  (ISO)
4,4'-sulfonyldiphenol  (EXP)
6-propyl-2-thiouracil  (ISO)
acetamide  (ISO)
acrylamide  (EXP,ISO)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (EXP)
amiodarone  (EXP)
ammonium chloride  (ISO)
arsane  (EXP)
arsenic atom  (EXP)
arsenite(3-)  (EXP)
benzene  (ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[a]pyrene diol epoxide I  (EXP)
benzo[b]fluoranthene  (ISO)
beta-lapachone  (EXP)
bis(2-chloroethyl) sulfide  (EXP)
bisphenol A  (EXP,ISO)
bortezomib  (EXP)
cadmium dichloride  (EXP,ISO)
calcitriol  (EXP)
carbamazepine  (EXP)
chlorpyrifos  (ISO)
choline  (ISO)
chromium(6+)  (EXP,ISO)
cocaine  (ISO)
copper atom  (EXP,ISO)
copper(0)  (EXP,ISO)
copper(II) sulfate  (EXP)
corticosterone  (ISO)
coumestrol  (EXP)
crocidolite asbestos  (EXP)
CU-O LINKAGE  (EXP)
Cuprizon  (ISO)
cyclosporin A  (EXP,ISO)
DDE  (EXP)
diallyl trisulfide  (EXP)
dibenz[a,h]anthracene  (ISO)
dibutyl phthalate  (ISO)
diethyl maleate  (ISO)
dioxygen  (EXP)
doxorubicin  (EXP)
endosulfan  (ISO)
Enterolactone  (EXP)
fenofibrate  (ISO)
folic acid  (EXP,ISO)
FR900359  (EXP)
fulvestrant  (EXP)
gentamycin  (ISO)
hydrogen peroxide  (EXP)
ivermectin  (EXP)
L-methionine  (ISO)
lead(0)  (EXP)
leflunomide  (EXP)
lidocaine  (ISO)
linezolid  (ISO)
lithium atom  (ISO)
lithium hydride  (ISO)
lucanthone  (EXP)
MeIQx  (EXP)
mercury dichloride  (ISO)
methamphetamine  (EXP)
methapyrilene  (ISO)
methotrexate  (EXP)
N-methyl-4-phenylpyridinium  (EXP)
N-Nitrosopyrrolidine  (EXP)
niclosamide  (EXP)
oxaliplatin  (ISO)
ozone  (ISO)
palbociclib  (EXP)
paracetamol  (EXP,ISO)
PCB138  (ISO)
perfluorohexanesulfonic acid  (ISO)
perfluorooctanoic acid  (EXP)
phenanthridone  (EXP)
pirinixic acid  (ISO)
potassium dichromate  (EXP)
pregnenolone 16alpha-carbonitrile  (ISO)
propanal  (EXP)
quercetin  (ISO)
silicon dioxide  (ISO)
sirolimus  (ISO)
sodium arsenite  (EXP)
sunitinib  (EXP)
tacrolimus hydrate  (ISO)
temozolomide  (EXP)
tert-butyl hydroperoxide  (EXP)
testosterone  (EXP,ISO)
thapsigargin  (ISO)
thioacetamide  (ISO)
thiram  (EXP)
titanium dioxide  (ISO)
topotecan  (ISO)
trichloroethene  (ISO)
trimellitic anhydride  (ISO)
triptonide  (ISO)
tunicamycin  (EXP)
valproic acid  (EXP)
zoledronic acid  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. GOAs Human GO annotations GOA_HUMAN data from the GO Consortium
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
3. Transcriptomic characteristics of bronchoalveolar lavage fluid and peripheral blood mononuclear cells in COVID-19 patients. Xiong Y, etal., Emerg Microbes Infect. 2020 Dec;9(1):761-770. doi: 10.1080/22221751.2020.1747363.
Additional References at PubMed
PMID:8276466   PMID:10369922   PMID:11416179   PMID:12477932   PMID:14574404   PMID:15489334   PMID:15843429   PMID:17081983   PMID:17326138   PMID:18082152   PMID:19116309   PMID:19190132  
PMID:19525938   PMID:19679349   PMID:19851445   PMID:19946888   PMID:21832049   PMID:21873635   PMID:22201025   PMID:22946058   PMID:23318213   PMID:24039245   PMID:24711643   PMID:24857844  
PMID:24981860   PMID:25028599   PMID:25281560   PMID:25788277   PMID:26177331   PMID:26186194   PMID:26344197   PMID:26389662   PMID:26496610   PMID:26641092   PMID:26831064   PMID:26987684  
PMID:26992853   PMID:27114546   PMID:27176706   PMID:27665358   PMID:27777970   PMID:28186131   PMID:28209915   PMID:28218233   PMID:28430595   PMID:28514442   PMID:28885720   PMID:28964573  
PMID:29562961   PMID:29564676   PMID:29568061   PMID:29620256   PMID:29656893   PMID:29684553   PMID:29844126   PMID:29985404   PMID:30021884   PMID:30066085   PMID:30115976   PMID:30217970  
PMID:30884312   PMID:30948266   PMID:31048545   PMID:31091453   PMID:31127080   PMID:31278883   PMID:31340839   PMID:31434716   PMID:31470122   PMID:31527615   PMID:31904480   PMID:32129710  
PMID:32160526   PMID:32707033   PMID:32753405   PMID:32807901   PMID:33034273   PMID:33306668   PMID:33361741   PMID:33397691   PMID:33397932   PMID:33640491   PMID:33729478   PMID:33742100  
PMID:33760984   PMID:33961781   PMID:34079125   PMID:34148003   PMID:34189442   PMID:35013218   PMID:35013556   PMID:35140242   PMID:35143306   PMID:35271311   PMID:35479190   PMID:35509820  
PMID:35915203   PMID:35944360   PMID:36089195   PMID:36215168   PMID:36373674   PMID:36424410   PMID:36526897   PMID:36574265   PMID:36990154   PMID:37108203   PMID:37314180   PMID:37666088  
PMID:37827155   PMID:38003261   PMID:38112634   PMID:38456590   PMID:38551642   PMID:38777146   PMID:38902769   PMID:38943005  


Genomics

Comparative Map Data
KIFC1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38633,391,461 - 33,409,896 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl633,391,823 - 33,409,896 (+)EnsemblGRCh38hg38GRCh38
GRCh37633,359,600 - 33,377,673 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36633,467,583 - 33,485,625 (+)NCBINCBI36Build 36hg18NCBI36
Celera634,913,703 - 34,932,095 (+)NCBICelera
Cytogenetic Map6p21.32NCBI
HuRef633,101,381 - 33,119,773 (+)NCBIHuRef
CHM1_1633,361,187 - 33,379,567 (+)NCBICHM1_1
T2T-CHM13v2.0633,212,742 - 33,231,258 (+)NCBIT2T-CHM13v2.0
Kifc1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391734,094,640 - 34,109,607 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1734,094,633 - 34,109,635 (-)EnsemblGRCm39 Ensembl
GRCm381733,875,664 - 33,890,633 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1733,875,659 - 33,890,661 (-)EnsemblGRCm38mm10GRCm38
MGSCv371734,011,931 - 34,042,544 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361727,054,036 - 27,069,524 (+)NCBIMGSCv36mm8
Celera1736,628,582 - 36,643,546 (-)NCBICelera
Cytogenetic Map17B1NCBI
cM Map1717.98NCBI
Kifc1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8205,000,929 - 5,018,967 (+)NCBIGRCr8
mRatBN7.2204,998,832 - 5,017,107 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl204,999,047 - 5,017,105 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx205,722,546 - 5,742,381 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0205,084,291 - 5,104,118 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0205,564,478 - 5,582,550 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0205,509,059 - 5,526,175 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl205,509,059 - 5,526,175 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0207,567,671 - 7,585,188 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4205,150,810 - 5,169,264 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1205,151,036 - 5,169,489 (+)NCBI
Celera206,581,869 - 6,599,528 (+)NCBICelera
Cytogenetic Map20p12NCBI
Kifc1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554371,923,506 - 1,940,970 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554371,923,136 - 1,941,094 (+)NCBIChiLan1.0ChiLan1.0
KIFC1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2547,876,580 - 47,894,889 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1643,743,866 - 43,761,938 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0632,971,033 - 32,989,129 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1634,081,586 - 34,100,591 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl634,078,842 - 34,100,373 (+)Ensemblpanpan1.1panPan2
KIFC1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1122,808,374 - 2,821,203 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl122,808,705 - 2,821,217 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha122,889,201 - 2,901,948 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0123,140,027 - 3,152,781 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl123,140,220 - 3,152,876 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1122,807,166 - 2,819,907 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0122,888,268 - 2,901,012 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0122,986,376 - 2,999,127 (+)NCBIUU_Cfam_GSD_1.0
Kifc1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494638,457,125 - 38,472,793 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647625,487,503 - 25,546,359 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647625,488,426 - 25,503,135 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
KIFC1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl729,694,778 - 29,713,712 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1729,692,775 - 29,713,716 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2734,198,547 - 34,212,734 (+)NCBISscrofa10.2Sscrofa10.2susScr3
KIFC1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11738,656,517 - 38,675,056 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1738,656,246 - 38,674,470 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604433,240,536 - 33,258,617 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Kifc1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475423,410,007 - 23,413,902 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475423,405,951 - 23,421,696 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in KIFC1
44 total Variants

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 6p25.3-12.3(chr6:156974-46789291)x3 copy number gain See cases [RCV000143497] Chr6:156974..46789291 [GRCh38]
Chr6:156974..46757028 [GRCh37]
Chr6:101974..46864987 [NCBI36]
Chr6:6p25.3-12.3		 pathogenic
GRCh37/hg19 6p21.32(chr6:33256191-33400523)x3 copy number gain Breast ductal adenocarcinoma [RCV000207216] Chr6:33256191..33400523 [GRCh37]
Chr6:6p21.32		 uncertain significance
GRCh37/hg19 6p25.3-q27(chr6:156975-170919482)x3 copy number gain See cases [RCV000512067] Chr6:156975..170919482 [GRCh37]
Chr6:6p25.3-q27		 pathogenic
NM_002263.4(KIFC1):c.*15_*16dup insertion not specified [RCV000455622] Chr6:33409703..33409704 [GRCh38]
Chr6:33377480..33377481 [GRCh37]
Chr6:6p21.32		 benign
GRCh37/hg19 6p25.3-q27(chr6:156975-170919482) copy number gain See cases [RCV000510595] Chr6:156975..170919482 [GRCh37]
Chr6:6p25.3-q27		 pathogenic
NM_002263.4(KIFC1):c.1134C>G (p.Phe378Leu) single nucleotide variant not specified [RCV004321619] Chr6:33405229 [GRCh38]
Chr6:33373006 [GRCh37]
Chr6:6p21.32		 uncertain significance
NM_002263.4(KIFC1):c.19C>T (p.Pro7Ser) single nucleotide variant not specified [RCV004329193] Chr6:33398035 [GRCh38]
Chr6:33365812 [GRCh37]
Chr6:6p21.32		 uncertain significance
NC_000006.11:g.(?_33131435)_(33419703_?)dup duplication Intellectual disability, autosomal dominant 5 [RCV000817954] Chr6:33163658..33451926 [GRCh38]
Chr6:33131435..33419703 [GRCh37]
Chr6:6p21.32		 uncertain significance
GRCh37/hg19 6p25.3-q27(chr6:108666-170980171)x3 copy number gain not provided [RCV000745403] Chr6:108666..170980171 [GRCh37]
Chr6:6p25.3-q27		 pathogenic
GRCh37/hg19 6p25.3-q27(chr6:60107-171054786)x3 copy number gain not provided [RCV000745400] Chr6:60107..171054786 [GRCh37]
Chr6:6p25.3-q27		 pathogenic
GRCh37/hg19 6p25.3-q27(chr6:165632-170919470)x3 copy number gain not provided [RCV000745404] Chr6:165632..170919470 [GRCh37]
Chr6:6p25.3-q27		 pathogenic
GRCh37/hg19 6p22.1-q14.1(chr6:29455465-81447367) copy number gain not provided [RCV000767714] Chr6:29455465..81447367 [GRCh37]
Chr6:6p22.1-q14.1		 pathogenic
NC_000006.12:g.(?_33173681)_(33451926_?)dup duplication Intellectual disability, autosomal dominant 5 [RCV001032258] Chr6:33141458..33419703 [GRCh37]
Chr6:6p21.32		 uncertain significance
NC_000006.12:g.(?_33391986)_(33672228_?)dup duplication Intellectual disability, autosomal dominant 5 [RCV001032764] Chr6:33359763..33640005 [GRCh37]
Chr6:6p21.32-21.31		 uncertain significance
GRCh37/hg19 6p21.33-21.31(chr6:31036397-34088832)x3 copy number gain not provided [RCV001005791] Chr6:31036397..34088832 [GRCh37]
Chr6:6p21.33-21.31		 likely pathogenic
NM_002263.4(KIFC1):c.1846C>T (p.Arg616Trp) single nucleotide variant not specified [RCV004287674] Chr6:33406610 [GRCh38]
Chr6:33374387 [GRCh37]
Chr6:6p21.32		 uncertain significance
NM_002263.4(KIFC1):c.1669T>C (p.Cys557Arg) single nucleotide variant not specified [RCV004290825] Chr6:33406328 [GRCh38]
Chr6:33374105 [GRCh37]
Chr6:6p21.32		 uncertain significance
GRCh37/hg19 6p21.32-21.31(chr6:33069892-33751391) copy number gain not specified [RCV002053566] Chr6:33069892..33751391 [GRCh37]
Chr6:6p21.32-21.31		 uncertain significance
NC_000006.11:g.(?_30695893)_(36953949_?)dup duplication Proteasome-associated autoinflammatory syndrome 1 [RCV003113679] Chr6:30695893..36953949 [GRCh37]
Chr6:6p21.33-21.2		 uncertain significance
NM_002263.4(KIFC1):c.1082G>T (p.Ser361Ile) single nucleotide variant not specified [RCV004321487] Chr6:33405177 [GRCh38]
Chr6:33372954 [GRCh37]
Chr6:6p21.32		 uncertain significance
NM_002263.4(KIFC1):c.866G>A (p.Arg289His) single nucleotide variant not specified [RCV004111024] Chr6:33404961 [GRCh38]
Chr6:33372738 [GRCh37]
Chr6:6p21.32		 uncertain significance
NM_002263.4(KIFC1):c.44T>C (p.Ile15Thr) single nucleotide variant not specified [RCV004238426] Chr6:33398060 [GRCh38]
Chr6:33365837 [GRCh37]
Chr6:6p21.32		 likely benign
NM_002263.4(KIFC1):c.1735G>A (p.Gly579Ser) single nucleotide variant not specified [RCV004183242] Chr6:33406394 [GRCh38]
Chr6:33374171 [GRCh37]
Chr6:6p21.32		 uncertain significance
NM_002263.4(KIFC1):c.70G>T (p.Ala24Ser) single nucleotide variant not specified [RCV004102583] Chr6:33398086 [GRCh38]
Chr6:33365863 [GRCh37]
Chr6:6p21.32		 uncertain significance
NM_002263.4(KIFC1):c.1493C>T (p.Thr498Ile) single nucleotide variant not specified [RCV004130124] Chr6:33405588 [GRCh38]
Chr6:33373365 [GRCh37]
Chr6:6p21.32		 likely benign
NM_002263.4(KIFC1):c.728G>T (p.Gly243Val) single nucleotide variant not specified [RCV004128163] Chr6:33404101 [GRCh38]
Chr6:33371878 [GRCh37]
Chr6:6p21.32		 uncertain significance
NM_002263.4(KIFC1):c.1328C>G (p.Ser443Cys) single nucleotide variant not specified [RCV004229699] Chr6:33405423 [GRCh38]
Chr6:33373200 [GRCh37]
Chr6:6p21.32		 uncertain significance
NM_002263.4(KIFC1):c.274G>C (p.Gly92Arg) single nucleotide variant not specified [RCV004099860] Chr6:33403337 [GRCh38]
Chr6:33371114 [GRCh37]
Chr6:6p21.32		 uncertain significance
NM_002263.4(KIFC1):c.1385T>C (p.Val462Ala) single nucleotide variant not specified [RCV004181687] Chr6:33405480 [GRCh38]
Chr6:33373257 [GRCh37]
Chr6:6p21.32		 uncertain significance
NM_002263.4(KIFC1):c.448C>G (p.Leu150Val) single nucleotide variant not specified [RCV004071430] Chr6:33403821 [GRCh38]
Chr6:33371598 [GRCh37]
Chr6:6p21.32		 uncertain significance
NM_002263.4(KIFC1):c.154C>T (p.Arg52Trp) single nucleotide variant not specified [RCV004151988] Chr6:33398291 [GRCh38]
Chr6:33366068 [GRCh37]
Chr6:6p21.32		 uncertain significance
NM_002263.4(KIFC1):c.965C>T (p.Pro322Leu) single nucleotide variant not specified [RCV004157366] Chr6:33405060 [GRCh38]
Chr6:33372837 [GRCh37]
Chr6:6p21.32		 uncertain significance
NM_002263.4(KIFC1):c.994C>T (p.Leu332Phe) single nucleotide variant not specified [RCV004173234] Chr6:33405089 [GRCh38]
Chr6:33372866 [GRCh37]
Chr6:6p21.32		 uncertain significance
NC_000006.11:g.(?_32148920)_(36953949_?)dup duplication not provided [RCV003154914] Chr6:32148920..36953949 [GRCh37]
Chr6:6p21.32-21.2		 uncertain significance
NM_002263.4(KIFC1):c.1040G>A (p.Arg347His) single nucleotide variant not specified [RCV004267741] Chr6:33405135 [GRCh38]
Chr6:33372912 [GRCh37]
Chr6:6p21.32		 likely benign
NM_002263.4(KIFC1):c.1096C>A (p.Pro366Thr) single nucleotide variant not specified [RCV004268366] Chr6:33405191 [GRCh38]
Chr6:33372968 [GRCh37]
Chr6:6p21.32		 uncertain significance
NM_002263.4(KIFC1):c.841G>A (p.Ala281Thr) single nucleotide variant not specified [RCV004295414] Chr6:33404936 [GRCh38]
Chr6:33372713 [GRCh37]
Chr6:6p21.32		 likely benign
NM_002263.4(KIFC1):c.1102A>G (p.Thr368Ala) single nucleotide variant not specified [RCV004312821] Chr6:33405197 [GRCh38]
Chr6:33372974 [GRCh37]
Chr6:6p21.32		 uncertain significance
NM_002263.4(KIFC1):c.722G>A (p.Arg241Gln) single nucleotide variant not specified [RCV004279353] Chr6:33404095 [GRCh38]
Chr6:33371872 [GRCh37]
Chr6:6p21.32		 uncertain significance
NM_002263.4(KIFC1):c.1541A>G (p.Asp514Gly) single nucleotide variant not specified [RCV004348391] Chr6:33406200 [GRCh38]
Chr6:33373977 [GRCh37]
Chr6:6p21.32		 uncertain significance
NM_002263.4(KIFC1):c.1066C>T (p.Arg356Trp) single nucleotide variant not specified [RCV004343509] Chr6:33405161 [GRCh38]
Chr6:33372938 [GRCh37]
Chr6:6p21.32		 uncertain significance
NM_002263.4(KIFC1):c.856C>T (p.Arg286Trp) single nucleotide variant not specified [RCV004350028] Chr6:33404951 [GRCh38]
Chr6:33372728 [GRCh37]
Chr6:6p21.32		 uncertain significance
NM_002263.4(KIFC1):c.1562G>A (p.Arg521His) single nucleotide variant not specified [RCV004414366] Chr6:33406221 [GRCh38]
Chr6:33373998 [GRCh37]
Chr6:6p21.32		 likely benign
NM_002263.4(KIFC1):c.1658G>A (p.Arg553Gln) single nucleotide variant not specified [RCV004414368] Chr6:33406317 [GRCh38]
Chr6:33374094 [GRCh37]
Chr6:6p21.32		 uncertain significance
NM_002263.4(KIFC1):c.779C>T (p.Ala260Val) single nucleotide variant not specified [RCV004414375] Chr6:33404874 [GRCh38]
Chr6:33372651 [GRCh37]
Chr6:6p21.32		 uncertain significance
NM_002263.4(KIFC1):c.1601G>A (p.Arg534Gln) single nucleotide variant not specified [RCV004414367] Chr6:33406260 [GRCh38]
Chr6:33374037 [GRCh37]
Chr6:6p21.32		 uncertain significance
NM_002263.4(KIFC1):c.1931A>G (p.Glu644Gly) single nucleotide variant not specified [RCV004414372] Chr6:33406829 [GRCh38]
Chr6:33374606 [GRCh37]
Chr6:6p21.32		 uncertain significance
NM_002263.4(KIFC1):c.1366A>C (p.Ser456Arg) single nucleotide variant not specified [RCV004414364] Chr6:33405461 [GRCh38]
Chr6:33373238 [GRCh37]
Chr6:6p21.32		 uncertain significance
NM_002263.4(KIFC1):c.2011A>C (p.Asn671His) single nucleotide variant not specified [RCV004414373] Chr6:33409679 [GRCh38]
Chr6:33377456 [GRCh37]
Chr6:6p21.32		 uncertain significance
NM_002263.4(KIFC1):c.1748G>T (p.Arg583Leu) single nucleotide variant not specified [RCV004414370] Chr6:33406407 [GRCh38]
Chr6:33374184 [GRCh37]
Chr6:6p21.32		 uncertain significance
NM_002263.4(KIFC1):c.1778A>T (p.Asn593Ile) single nucleotide variant not specified [RCV004414371] Chr6:33406437 [GRCh38]
Chr6:33374214 [GRCh37]
Chr6:6p21.32		 uncertain significance
NM_002263.4(KIFC1):c.716A>T (p.Glu239Val) single nucleotide variant not specified [RCV004414374] Chr6:33404089 [GRCh38]
Chr6:33371866 [GRCh37]
Chr6:6p21.32		 uncertain significance
NM_002263.4(KIFC1):c.1138C>T (p.Pro380Ser) single nucleotide variant not specified [RCV004414361] Chr6:33405233 [GRCh38]
Chr6:33373010 [GRCh37]
Chr6:6p21.32		 uncertain significance
NM_002263.4(KIFC1):c.1466G>A (p.Arg489His) single nucleotide variant not specified [RCV004414365] Chr6:33405561 [GRCh38]
Chr6:33373338 [GRCh37]
Chr6:6p21.32		 likely benign
NM_002263.4(KIFC1):c.1121T>G (p.Phe374Cys) single nucleotide variant not specified [RCV004414360] Chr6:33405216 [GRCh38]
Chr6:33372993 [GRCh37]
Chr6:6p21.32		 uncertain significance
NM_002263.4(KIFC1):c.114G>T (p.Arg38Ser) single nucleotide variant not specified [RCV004414362] Chr6:33398130 [GRCh38]
Chr6:33365907 [GRCh37]
Chr6:6p21.32		 uncertain significance
NM_002263.4(KIFC1):c.1669T>G (p.Cys557Gly) single nucleotide variant not specified [RCV004414369] Chr6:33406328 [GRCh38]
Chr6:33374105 [GRCh37]
Chr6:6p21.32		 uncertain significance
NM_002263.4(KIFC1):c.1438G>C (p.Gly480Arg) single nucleotide variant not specified [RCV004636946] Chr6:33405533 [GRCh38]
Chr6:33373310 [GRCh37]
Chr6:6p21.32		 uncertain significance
NM_002263.4(KIFC1):c.281G>A (p.Arg94Gln) single nucleotide variant not specified [RCV004631493] Chr6:33403344 [GRCh38]
Chr6:33371121 [GRCh37]
Chr6:6p21.32		 uncertain significance
NM_002263.4(KIFC1):c.1741G>A (p.Gly581Arg) single nucleotide variant not specified [RCV004631494] Chr6:33406400 [GRCh38]
Chr6:33374177 [GRCh37]
Chr6:6p21.32		 uncertain significance
NC_000006.11:g.(?_33131455)_(33388128_?)dup duplication MHC class I deficiency [RCV004578657] Chr6:33131455..33388128 [GRCh37]
Chr6:6p21.32		 uncertain significance
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:928
Count of miRNA genes:438
Interacting mature miRNAs:481
Transcripts:ENST00000428849, ENST00000450504, ENST00000486695, ENST00000494554
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1358839MULTSCL5_HMultiple sclerosis susceptibility QTL 5 (human)Multiple sclerosis susceptibility61958431145584311Human
1298431RA11_HRheumatoid arthritis QTL 11 (human)0.0000024Joint/bone inflammationrheumatoid arthritis61991188340191709Human
1358857MULTSCL19_HMultiple sclerosis susceptibility QTL 19 (human)Multiple sclerosis susceptibility61958431145584311Human

Markers in Region
RH36517  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37633,374,617 - 33,374,803UniSTSGRCh37
Build 36633,482,595 - 33,482,781RGDNCBI36
Celera634,929,009 - 34,929,195RGD
Cytogenetic Map6p21.3UniSTS
HuRef633,116,685 - 33,116,871UniSTS
GeneMap99-GB4 RH Map6120.03UniSTS
NCBI RH Map6509.1UniSTS
AL035165  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37633,370,879 - 33,371,033UniSTSGRCh37
Build 36633,478,857 - 33,479,011RGDNCBI36
Celera634,925,271 - 34,925,425RGD
Cytogenetic Map6p21.3UniSTS
HuRef633,112,946 - 33,113,100UniSTS
D6S1834  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37633,377,536 - 33,377,673UniSTSGRCh37
Build 36633,485,514 - 33,485,651RGDNCBI36
Celera634,931,930 - 34,932,067RGD
Cytogenetic Map6p21.3UniSTS
HuRef633,119,608 - 33,119,745UniSTS
TNG Radiation Hybrid Map618521.0UniSTS
Stanford-G3 RH Map61775.0UniSTS
NCBI RH Map6509.1UniSTS
GeneMap99-G3 RH Map61907.0UniSTS
STS-D14678  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37633,377,533 - 33,377,689UniSTSGRCh37
Build 36633,485,511 - 33,485,667RGDNCBI36
Celera634,931,927 - 34,932,083RGD
Cytogenetic Map6p21.3UniSTS
HuRef633,119,605 - 33,119,761UniSTS
GeneMap99-GB4 RH Map6145.45UniSTS
NCBI RH Map6509.1UniSTS
UniSTS:236125  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37633,374,377 - 33,374,653UniSTSGRCh37
Build 36633,482,355 - 33,482,631RGDNCBI36
Celera634,928,769 - 34,929,045RGD
HuRef633,116,445 - 33,116,721UniSTS


Expression

RNA-SEQ Expression

adipose tissue
alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
entire extraembryonic component
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
pharyngeal arch
renal system
reproductive system
respiratory system
sensory system
visual system
1204 2439 2781 2246 4955 1722 2347 6 620 1950 461 2269 7281 6459 53 3718 1 849 1742 1617 175 1

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_002263 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011514585 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011514587 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017010836 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017010837 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054331077 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054331078 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054331079 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054331080 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054331081 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054331342 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054331343 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054331344 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054355374 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054355375 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054355376 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054355377 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054355378 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AI990093 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ010479 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK297378 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK303239 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL021366 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL050332 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL662799 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC000712 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC063567 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC073878 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC098438 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC121041 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC121042 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BE885900 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BX088650 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BX248088 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH471081 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CP068272 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CR759793 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  D14678 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KY500407 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KY500408 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KY500409 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENST00000428849   ⟹   ENSP00000393963
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl633,391,823 - 33,409,896 (+)Ensembl
Ensembl Acc Id: ENST00000450504   ⟹   ENSP00000409539
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl633,391,861 - 33,403,859 (+)Ensembl
Ensembl Acc Id: ENST00000486695
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl633,400,091 - 33,403,866 (+)Ensembl
Ensembl Acc Id: ENST00000494554   ⟹   ENSP00000484508
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl633,406,221 - 33,407,090 (+)Ensembl
RefSeq Acc Id: NM_002263   ⟹   NP_002254
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38633,391,823 - 33,409,896 (+)NCBI
GRCh37633,359,301 - 33,377,701 (+)NCBI
Build 36633,467,583 - 33,485,625 (+)NCBI Archive
Celera634,913,703 - 34,932,095 (+)RGD
HuRef633,101,381 - 33,119,773 (+)RGD
CHM1_1633,361,187 - 33,379,567 (+)NCBI
T2T-CHM13v2.0633,213,185 - 33,231,258 (+)NCBI
Sequence:
RefSeq Acc Id: XM_011514585   ⟹   XP_011512887
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38633,391,823 - 33,409,896 (+)NCBI
Sequence:
RefSeq Acc Id: XM_011514587   ⟹   XP_011512889
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38633,391,823 - 33,409,896 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017010837   ⟹   XP_016866326
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38633,391,461 - 33,409,896 (+)NCBI
Sequence:
RefSeq Acc Id: XM_054355374   ⟹   XP_054211349
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.0633,213,185 - 33,230,833 (+)NCBI
RefSeq Acc Id: XM_054355375   ⟹   XP_054211350
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.0633,213,185 - 33,231,258 (+)NCBI
RefSeq Acc Id: XM_054355376   ⟹   XP_054211351
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.0633,212,742 - 33,230,833 (+)NCBI
RefSeq Acc Id: XM_054355377   ⟹   XP_054211352
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.0633,213,185 - 33,230,833 (+)NCBI
RefSeq Acc Id: XM_054355378   ⟹   XP_054211353
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.0633,213,185 - 33,231,258 (+)NCBI
Protein Sequences
Protein RefSeqs NP_002254 (Get FASTA)   NCBI Sequence Viewer  
  XP_011512887 (Get FASTA)   NCBI Sequence Viewer  
  XP_011512889 (Get FASTA)   NCBI Sequence Viewer  
  XP_016866326 (Get FASTA)   NCBI Sequence Viewer  
  XP_054187052 (Get FASTA)   NCBI Sequence Viewer  
  XP_054187053 (Get FASTA)   NCBI Sequence Viewer  
  XP_054187054 (Get FASTA)   NCBI Sequence Viewer  
  XP_054187055 (Get FASTA)   NCBI Sequence Viewer  
  XP_054187056 (Get FASTA)   NCBI Sequence Viewer  
  XP_054187317 (Get FASTA)   NCBI Sequence Viewer  
  XP_054187318 (Get FASTA)   NCBI Sequence Viewer  
  XP_054187319 (Get FASTA)   NCBI Sequence Viewer  
  XP_054211349 (Get FASTA)   NCBI Sequence Viewer  
  XP_054211350 (Get FASTA)   NCBI Sequence Viewer  
  XP_054211351 (Get FASTA)   NCBI Sequence Viewer  
  XP_054211352 (Get FASTA)   NCBI Sequence Viewer  
  XP_054211353 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH00712 (Get FASTA)   NCBI Sequence Viewer  
  AAH63567 (Get FASTA)   NCBI Sequence Viewer  
  AAH73878 (Get FASTA)   NCBI Sequence Viewer  
  AAH98438 (Get FASTA)   NCBI Sequence Viewer  
  AAI21042 (Get FASTA)   NCBI Sequence Viewer  
  AAI21043 (Get FASTA)   NCBI Sequence Viewer  
  AQY76894 (Get FASTA)   NCBI Sequence Viewer  
  AQY76895 (Get FASTA)   NCBI Sequence Viewer  
  AQY76896 (Get FASTA)   NCBI Sequence Viewer  
  BAA03509 (Get FASTA)   NCBI Sequence Viewer  
  BAG59820 (Get FASTA)   NCBI Sequence Viewer  
  BAG64325 (Get FASTA)   NCBI Sequence Viewer  
  CAA09217 (Get FASTA)   NCBI Sequence Viewer  
  CAA16157 (Get FASTA)   NCBI Sequence Viewer  
  CAB63782 (Get FASTA)   NCBI Sequence Viewer  
  EAX03726 (Get FASTA)   NCBI Sequence Viewer  
  EAX03727 (Get FASTA)   NCBI Sequence Viewer  
  EAX03728 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSP00000363647.4
  ENSP00000393963
  ENSP00000393963.2
  ENSP00000400323.1
  ENSP00000407885.2
  ENSP00000409539.1
  ENSP00000415907.1
  ENSP00000484508.1
GenBank Protein Q9BW19 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_002254   ⟸   NM_002263
- UniProtKB: Q6P4A5 (UniProtKB/Swiss-Prot),   Q6GMS7 (UniProtKB/Swiss-Prot),   Q5SU09 (UniProtKB/Swiss-Prot),   Q4KMP0 (UniProtKB/Swiss-Prot),   Q14834 (UniProtKB/Swiss-Prot),   O60887 (UniProtKB/Swiss-Prot),   Q9UQP7 (UniProtKB/Swiss-Prot),   Q9BW19 (UniProtKB/Swiss-Prot),   A0A024RCS7 (UniProtKB/TrEMBL),   A0A1U9X7X5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_011512887   ⟸   XM_011514585
- Peptide Label: isoform X1
- UniProtKB: A0A1U9X7X5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_011512889   ⟸   XM_011514587
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_016866326   ⟸   XM_017010837
- Peptide Label: isoform X3
- UniProtKB: A0A1U9X7X5 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSP00000409539   ⟸   ENST00000450504
Ensembl Acc Id: ENSP00000393963   ⟸   ENST00000428849
Ensembl Acc Id: ENSP00000484508   ⟸   ENST00000494554
RefSeq Acc Id: XP_054211351   ⟸   XM_054355376
- Peptide Label: isoform X8
- UniProtKB: A0A1U9X7X5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_054211350   ⟸   XM_054355375
- Peptide Label: isoform X1
- UniProtKB: A0A1U9X7X5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_054211353   ⟸   XM_054355378
- Peptide Label: isoform X2
RefSeq Acc Id: XP_054211349   ⟸   XM_054355374
- Peptide Label: isoform X7
- UniProtKB: A0A1U9X7X5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_054211352   ⟸   XM_054355377
- Peptide Label: isoform X9
Protein Domains
Kinesin motor

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9BW19-F1-model_v2 AlphaFold Q9BW19 1-673 view protein structure

Promoters
RGD ID:6872884
Promoter ID:EPDNEW_H9607
Type:initiation region
Name:KIFC1_1
Description:kinesin family member C1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H9608  
Experiment Methods:Single-end sequencing.; Paired-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh38633,391,533 - 33,391,593EPDNEW
RGD ID:6872886
Promoter ID:EPDNEW_H9608
Type:initiation region
Name:KIFC1_2
Description:kinesin family member C1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H9607  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh38633,391,859 - 33,391,919EPDNEW
RGD ID:6804397
Promoter ID:HG_KWN:53201
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   CD4+TCell_12Hour,   CD4+TCell_2Hour,   HeLa_S3,   Jurkat,   K562,   Lymphoblastoid,   NB4
Transcripts:OTTHUMT00000076417,   OTTHUMT00000276421
Position:
Human AssemblyChrPosition (strand)Source
Build 36633,467,041 - 33,467,687 (+)MPROMDB
RGD ID:6804398
Promoter ID:HG_KWN:53203
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:HeLa_S3,   Jurkat,   K562,   Lymphoblastoid,   NB4
Transcripts:OTTHUMT00000276423
Position:
Human AssemblyChrPosition (strand)Source
Build 36633,481,106 - 33,482,412 (+)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:6389 AgrOrtholog
COSMIC KIFC1 COSMIC
Ensembl Genes ENSG00000204197 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSG00000233450 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSG00000237649 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENST00000374523.8 UniProtKB/Swiss-Prot
  ENST00000411963.1 UniProtKB/TrEMBL
  ENST00000426791.1 UniProtKB/TrEMBL
  ENST00000428849 ENTREZGENE
  ENST00000428849.7 UniProtKB/Swiss-Prot
  ENST00000448818.6 UniProtKB/Swiss-Prot
  ENST00000450504.1 UniProtKB/TrEMBL
  ENST00000494554.2 UniProtKB/TrEMBL
Gene3D-CATH 1.10.287.1490 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.40.850.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
GTEx ENSG00000204197 GTEx
  ENSG00000233450 GTEx
  ENSG00000237649 GTEx
HGNC ID HGNC:6389 ENTREZGENE
Human Proteome Map KIFC1 Human Proteome Map
InterPro Kinesin-like_fam UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Kinesin_motor_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Kinesin_motor_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Kinesin_motor_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report hsa:3833 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene 3833 ENTREZGENE
OMIM 603763 OMIM
PANTHER KINESIN-LIKE PROTEIN KLP-3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PROTEIN CLARET SEGREGATIONAL UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Kinesin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB PA30178 PharmGKB
PRINTS KINESINHEAVY UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE KINESIN_MOTOR_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  KINESIN_MOTOR_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RNAcentral URS00009AFA8E RNACentral
  URS00009BCD59 RNACentral
SMART KISc UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF52540 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A024RCS7 ENTREZGENE, UniProtKB/TrEMBL
  A0A087X1W5_HUMAN UniProtKB/TrEMBL
  A0A140T9E6_HUMAN UniProtKB/TrEMBL
  A0A1U9X7X5 ENTREZGENE, UniProtKB/TrEMBL
  A2AB20_HUMAN UniProtKB/TrEMBL
  KIFC1_HUMAN UniProtKB/Swiss-Prot
  O60887 ENTREZGENE
  Q14834 ENTREZGENE
  Q4KMP0 ENTREZGENE
  Q5SU09 ENTREZGENE
  Q6GMS7 ENTREZGENE
  Q6P4A5 ENTREZGENE
  Q9BW19 ENTREZGENE
  Q9UQP7 ENTREZGENE
UniProt Secondary O60887 UniProtKB/Swiss-Prot
  Q14834 UniProtKB/Swiss-Prot
  Q4KMP0 UniProtKB/Swiss-Prot
  Q5SU09 UniProtKB/Swiss-Prot
  Q6GMS7 UniProtKB/Swiss-Prot
  Q6P4A5 UniProtKB/Swiss-Prot
  Q9UQP7 UniProtKB/Swiss-Prot