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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1550478
Species: Mus musculus
RGD Object: Gene
Symbol: Gnao1
Name: guanine nucleotide binding protein, alpha O
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Gnao1decreases expressionEXP 6480464CTDbisphenol A results in decreased expression of GNAO1 mRNAPMID:32156529
Gnao1decreases expressionISOGnao1 (Rattus norvegicus)6480464CTDbisphenol A results in decreased expression of GNAO1 mRNAPMID:25181051 PMID:30816183
Gnao1decreases expressionISOGNAO1 (Homo sapiens)6480464CTDbisphenol A results in decreased expression of GNAO1 proteinPMID:33376534
Gnao1increases methylationISOGnao1 (Rattus norvegicus)6480464CTDbisphenol A results in increased methylation of GNAO1 genePMID:28505145
Gnao1multiple interactionsISOGnao1 (Rattus norvegicus)6480464CTD[bisphenol A co-treated with Testosterone] results in decreased expression of GNAO1 mRNAPMID:26496021
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