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GENE - TERM ANNOTATION REPORT

RGD ID: 14146900
Species: Sus scrofa
RGD Object: Gene
Symbol: CXCL9
Name: C-X-C motif chemokine ligand 9
Acc ID: DOID:0081267
Term: graft-versus-host disease
Definition: An immune system disease that is characterized by recognition by mature donor T cells, that contaminate the allogeneic bone marrow, of the recipient's tissue as foreign, causing a severe inflammatory disease characterized by rashes, diarrhea, and liver disease, and that has_material_basis_in an associated with variation in the interleukin-10 gene (IL10) on chromosome 1q32. (DO)
Definition Source(s): https://pubmed.ncbi.nlm.nih.gov/31466596/ "DO" "DO", https://www.ncbi.nlm.nih.gov/books/NBK538235/ "DO" "DO"
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
CXCL9 ISOCxcl9 (Mus musculus)9068941RGDmRNA, protein:increased expression:intestine, liver, lungPMID:19218194 REF_RGD_ID:5135435
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