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GENE - TERM ANNOTATION REPORT

RGD ID: 14134172
Species: Sus scrofa
RGD Object: Gene
Symbol: CASP3
Name: caspase 3
Acc ID: GO:0004197
Term: cysteine-type endopeptidase activity
Definition: Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile.
Definition Source(s): GOC:mah, https://www.ebi.ac.uk/merops/about/glossary.shtml#CATTYPE, https://www.ebi.ac.uk/merops/about/glossary.shtml#ENDOPEPTIDASE
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
CASP3enablesIEAUniProtKB:P42574 or UniProtKB:P70677 or ensembl:ENSMUSP00000147767 or ensembl:ENSP00000311032150520179Ensembl GO_REF:0000107
CASP3enablesIBAFB:FBgn0010501 or FB:FBgn0019972 or FB:FBgn0020381 or FB:FBgn0028381 or FB:FBgn0033659 or MGI:107700 or MGI:107739 or MGI:109383 or MGI:1261423 or MGI:1277950 or MGI:1312922 or MGI:97295 or PANTHER:PTN000047947 or Casp8 (Rattus norvegicus) or UniProtKB:A0A1D5PPP7 or UniProtKB:F1NV61 or UniProtKB:P42574 or UniProtKB:P42575 or UniProtKB:P49662 or UniProtKB:P51878 or UniProtKB:P55210 or UniProtKB:P55211 or UniProtKB:P55212 or UniProtKB:Q14790 or UniProtKB:Q92851 or WB:WBGene00000417 or ZFIN:ZDB-GENE-000616-3 or ZFIN:ZDB-GENE-020812-1150520179GO_Central GO_REF:0000033
CASP3enablesIEAInterPro:IPR001309 or InterPro:IPR002138 or InterPro:IPR002398 or InterPro:IPR011600150520179InterPro GO_REF:0000002
CASP3enablesISSUniProtKB:P42574150520179UniProt GO_REF:0000024
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