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GENE - TERM ANNOTATION REPORT

RGD ID: 14056892
Species: Sus scrofa
RGD Object: Gene
Symbol: CCL2
Name: chemokine (C-C motif) ligand 2
Acc ID: DOID:13100
Term: intracranial vasospasm
Definition: Constriction of arteries in the SKULL due to sudden, sharp, and often persistent smooth muscle contraction in blood vessels. Intracranial vasospasm results in reduced vessel lumen caliber, restricted blood flow to the brain, and BRAIN ISCHEMIA that may lead to hypoxic-ischemic brain injury (HYPOXIA-ISCHEMIA, BRAIN).
Definition Source(s): MESH:D020301
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
CCL2 ISOCcl2 (Rattus norvegicus)9068941RGDassociated with Subarachnoid Hemorrhage;mRNA, protein:increased expression:basilar arteryPMID:19401162 REF_RGD_ID:2306995
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