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GENE - TERM ANNOTATION REPORT

RGD ID: 14000091
Species: Sus scrofa
RGD Object: Gene
Symbol: ECE1
Name: endothelin converting enzyme 1
Acc ID: DOID:10763
Term: hypertension
Definition: An artery disease characterized by chronic elevated blood pressure in the arteries. (DO)
Definition Source(s): https://en.wikipedia.org/wiki/Hypertension "DO" "DO", https://www.ncbi.nlm.nih.gov/pubmed/24352797 "DO" "DO"
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
ECE1 ISOEce1 (Rattus norvegicus)9068941RGD PMID:12193123 REF_RGD_ID:1580907
ECE1 ISOEce1 (Rattus norvegicus)9068941RGDmRNA,protein:increased expression,increased activity:kidney medullaPMID:10894793 REF_RGD_ID:7244182
ECE1 ISOECE1 (Homo sapiens)9068941RGD PMID:15126915 REF_RGD_ID:1580904
ECE1 ISOECE1 (Homo sapiens)9068941CTDCTD Direct Evidence: marker/mechanismPMID:12566389
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