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GENE - TERM ANNOTATION REPORT

RGD ID: 13905820
Species: Sus scrofa
RGD Object: Gene
Symbol: MYOC
Name: myocilin
Acc ID: DOID:9282
Term: ocular hypertension
Definition: An eye disease that is characterized by elevated intraocular pressure in the absence of optic nerve damage or visual field loss. (DO)
Definition Source(s): https://en.wikipedia.org/wiki/Ocular_hypertension "DO" "DO"
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
MYOC ISOMyoc (Rattus norvegicus)9068941RGDmRNA:increased expression:retina (rat)PMID:17102796 REF_RGD_ID:1601004
MYOC ISOMyoc (Mus musculus)9068941RGDmRNA:decreased expression:eye, trabecular mesh (mouse)PMID:23322580 REF_RGD_ID:7394804
MYOC ISOMYOC (Homo sapiens)9068941RGDassociated with Glaucoma, Primary Open Angle; DNA:snp:cds:p.T377M (human)PMID:20107173 REF_RGD_ID:7394831
MYOCtreatmentISOMyoc (Mus musculus)9068941RGD PMID:23322580 REF_RGD_ID:7394804
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