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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1352962
Species: Homo sapiens
RGD Object: Gene
Symbol: CYP3A4
Name: cytochrome P450 family 3 subfamily A member 4
Acc ID: CHEBI:42053
Term: nemorubicin
Definition: An anthracycline antibiotic that has formula C32H37NO13.
Chemical ID: MESH:C066998
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
CYP3A4increases metabolic processingEXP 6480464CTDCYP3A4 protein results in increased metabolism of methoxy-morpholinyl-doxorubicinPMID:15465924
CYP3A4multiple interactionsEXP 6480464CTD[CYP3A4 protein co-treated with POR protein] results in increased metabolism of methoxy-morpholinyl-doxorubicinPMID:15465924
CYP3A4increases metabolic processingISOCyp3a2 (Rattus norvegicus)6480464CTDCYP3A2 protein results in increased metabolism of methoxy-morpholinyl-doxorubicinPMID:15465924
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