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GENE - TERM ANNOTATION REPORT

RGD ID: 1350372
Species: Homo sapiens
RGD Object: Gene
Symbol: VPS35
Name: VPS35 retromer complex component
Acc ID: DOID:0060897
Term: Parkinson's disease 17
Definition: A late-onset Parkinson disease that has_material_basis_in heterozygous mutation in the VPS35 gene on chromosome 16q13. (DO)
Definition Source(s): https://www.ncbi.nlm.nih.gov/pubmed/21763483 "DO" "DO"
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
VPS35 IAGP 7240710OMIM  
VPS35 IAGP (Homo sapiens) or (Homo sapiens) or (Homo sapiens) or (Homo sapiens) or (Homo sapiens) or (Homo sapiens) or (Homo sapiens) or (Homo sapiens) or (Homo sapiens) or (Homo sapiens) or (Homo sapiens) or (Homo sapiens) or (Homo sapiens) or (Homo sapiens) or (Homo sapiens) or (Homo sapiens) or (Homo sapiens) or (Homo sapiens) or (Homo sapiens) or (Homo sapiens) or (Homo sapiens)8554872ClinVarClinVar Annotator: match by term: Parkinson disease 17 
VPS35 IAGP (Homo sapiens) or (Homo sapiens) or (Homo sapiens) or (Homo sapiens)8554872ClinVarClinVar Annotator: match by term: Parkinson disease 17PMID:25741868
VPS35 IAGP (Homo sapiens) or (Homo sapiens) or (Homo sapiens) or (Homo sapiens) or (Homo sapiens) or (Homo sapiens) or (Homo sapiens) or (Homo sapiens) or (Homo sapiens) or (Homo sapiens)8554872ClinVarClinVar Annotator: match by term: Parkinson disease 17 | ClinVar Annotator: match by term: VPS35-related conditionPMID:25741868 PMID:28492532
VPS35 IAGP (Homo sapiens) or (Homo sapiens) or (Homo sapiens) or (Homo sapiens) or (Homo sapiens) or (Homo sapiens) or (Homo sapiens) or (Homo sapiens) or (Homo sapiens) or (Homo sapiens) or (Homo sapiens) or (Homo sapiens) or (Homo sapiens) or (Homo sapiens) or (Homo sapiens) or (Homo sapiens) or (Homo sapiens) or (Homo sapiens) or (Homo sapiens) or (Homo sapiens) or (Homo sapiens) or (Homo sapiens) or (Homo sapiens) or (Homo sapiens) or (Homo sapiens) or (Homo sapiens) or (Homo sapiens) or (Homo sapiens) or (Homo sapiens) or (Homo sapiens) or (Homo sapiens) or (Homo sapiens) or (Homo sapiens) or (Homo sapiens) or (Homo sapiens) or (Homo sapiens) or (Homo sapiens) or (Homo sapiens) or (Homo sapiens) or (Homo sapiens) or (Homo sapiens) or (Homo sapiens) or (Homo sapiens) or (Homo sapiens) or (Homo sapiens) or (Homo sapiens) or (Homo sapiens) or (Homo sapiens) or (Homo sapiens) or (Homo sapiens) or (Homo sapiens) or (Homo sapiens) or (Homo sapiens) or (Homo sapiens) or (Homo sapiens) or (Homo sapiens) or (Homo sapiens) or (Homo sapiens) or (Homo sapiens) or (Homo sapiens) or (Homo sapiens) or (Homo sapiens) or (Homo sapiens) or (Homo sapiens) or (Homo sapiens) or (Homo sapiens) or (Homo sapiens) or (Homo sapiens) or (Homo sapiens) or (Homo sapiens) or (Homo sapiens) or (Homo sapiens) or (Homo sapiens) or (Homo sapiens) or (Homo sapiens) or (Homo sapiens) or (Homo sapiens) or (Homo sapiens) or (Homo sapiens) or (Homo sapiens) or (Homo sapiens) or (Homo sapiens) or (Homo sapiens) or (Homo sapiens) or (Homo sapiens) or (Homo sapiens) or (Homo sapiens) or (Homo sapiens) or (Homo sapiens) or (Homo sapiens) or (Homo sapiens) or (Homo sapiens) or (Homo sapiens) or (Homo sapiens) or (Homo sapiens)8554872ClinVarClinVar Annotator: match by term: Parkinson disease 17 | ClinVar Annotator: match by term: VPS35-related conditionPMID:28492532
VPS35 IAGP (Homo sapiens)8554872ClinVarClinVar Annotator: match by term: Parkinson disease 17PMID:28166811 PMID:28492532
VPS35 IAGP (Homo sapiens)8554872ClinVarClinVar Annotator: match by term: Parkinson disease 17PMID:21763482 PMID:23408866 PMID:23536430 PMID:24740878 PMID:25288323 PMID:25533483 PMID:25741868 PMID:26321632 PMID:27385586 PMID:27964832 PMID:28222538 PMID:28492532 PMID:28796472 PMID:37786555
VPS35 IAGP (Homo sapiens) or (Homo sapiens) or (Homo sapiens) or (Homo sapiens) or (Homo sapiens) or (Homo sapiens) or (Homo sapiens) or (Homo sapiens)8554872ClinVarClinVar Annotator: match by term: Parkinson disease 17PMID:28796472
VPS35 IAGP (Homo sapiens)8554872ClinVarClinVar Annotator: match by term: Parkinson disease 17PMID:21763482 PMID:28492532 PMID:28796472 PMID:32613234
VPS35 IAGP (Homo sapiens)8554872ClinVarClinVar Annotator: match by term: Parkinson disease 17PMID:23125461 PMID:25288323 PMID:26251041 PMID:28492532 PMID:28796472 PMID:28862745
VPS35 IAGP (Homo sapiens)8554872ClinVarClinVar Annotator: match by term: Parkinson disease 17PMID:25741868 PMID:28492532 PMID:28796472
VPS35 IAGP (Homo sapiens) or (Homo sapiens)8554872ClinVarClinVar Annotator: match by term: Parkinson disease 17PMID:17576681 PMID:28492532 PMID:9536098
VPS35 IAGP (Homo sapiens)8554872ClinVarClinVar Annotator: match by term: Parkinson disease 17PMID:18342564 PMID:21763482 PMID:21763483 PMID:22154191 PMID:22517097 PMID:22801713 PMID:22991136 PMID:23411763 PMID:24740878 PMID:25741868 PMID:28492532 PMID:28796472
VPS35 ISSVps35 (Mus musculus)13592920MouseDOOMIM:614203 
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